Saturday, 6 April 2019

Honey Improved the Digestive Functioning

By Kyle J. Norton


Digestion is a process of the digestive system by breaking out down food after intake for nutrients through mechanical and enzymatic action.

Indigestion, on the other hand, is symptoms of another digestive disease, including GERD. Most cases of indigestion not caused by underlying diseases can be resolved quickly.

People with indigestion experience symptoms differently. Some may feel the symptoms of occasionally while others may feel often and daily.

There are a number of risk factor associated with digestive disorders including bacterial and/or viral infection, inflammation, lactase deficiency, anti-inflammatory drugs and certain conditions such as ruptured or perforated organs, muscle dysfunction, gallstones.

However, some researchers suggested that there is a strong correlation between the risk of digestive disorders in obese patients.

Dr. Su Youn Nam, in the investigation of obesity-related digestive diseases, wrote, "Obesity-related digestive diseases include gastroesophageal reflux disease, Barrett’s esophagus, esophageal cancer, colon polyp and cancer, nonalcoholic fatty liver disease, hepatitis C-related disease, hepatocellular carcinoma, gallstone, cholangiocarcinoma, and pancreatic cancer".

And, "Although obesity-related esophageal diseases are associated with altered mechanical and humoral factors, other obesity-related digestive diseases seem to be associated with obesity-induced altered circulating levels of adipocytokines and insulin resistance".

The findings strongly indicated the risk of digestive disorder in obese is substantially higher compared to healthy weight individuals.

Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers.

The liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Scientists on the finding a natural ingredient for the treatment of gastroduodenal (GDD) digestions examined the effect of Manuka honey antibacterial activity on tested strains.

In vitro, methylglyoxal (MGO), a bioactive found in Manuka honey injection showed a strong antibacterial activity at concentrations higher than those registered in digested MH samples.

The findings suggested that there must be some other compounds in the Manuka honey which also process the antibacterial property.

In fact, according to the tested assays in the modification of the chemicals occurring from digestion, the content of aromatic compounds, such as leptosin and methyl syringate which played a critical role in increasing the levels of acetic and lactic acids in gastroduodenal digestion.

The results suggested that Manuka honey promoted gastroduodenal digestion through a number of metabolites.

In order to provide more information about Manuka honey in the promotion of digestion, researchers investigated its effects on gastrointestinal infection diseases and upper gastrointestinal dyspepsia.

The study included several commercial MH samples, with different MGO concentrations.

According to the tested assays, after digestion, MGO concentration decreases because it reacts with digestive enzymes by carbonylating their free amino groups in stimulating the gastric phase of digestion.

And other compounds in Manuka honey such as pepsin and pancreatin does not influence the digestion process.

In other words, methylglyoxal (MGO) promotes gastrointestinal digestion through its pronounced antibacterial potency.

Taken altogether, Manuka honey processed a bioactive compound MGO may be considered a natural remedy for improvement of digestion, pending to the validation of larger sample size and multicenter human study


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Antistaphylococcal activity and metabolite profiling of manuka honey(Leptospermum scoparium L.) after in vitro simulated digestion by Mannina L1, Sobolev AP2, Coppo E3, Di Lorenzo A4, Nabavi SM5, Marchese A3, Daglia M. (PubMed)
(2) Influence of in vitro simulated gastroduodenal digestion on methylglyoxal concentration of Manuka ( Lectospermum scoparium ) honey by Daglia M1, Ferrari D, Collina S, Curti V. (PubMed)

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