Saturday, 20 April 2019

Herbal Artichoke, Protects Your Upper Digestive Tract Against Functional Dyspepsia (FD)

By Kyle J. Norton

Functional dyspepsia (FD) is a chronic condition characterized by burning sensation caused by uncoordinated and ineffectual emptying of the upper digestive tract with no measurable structural abnormalities.

Functional dyspepsia (FD) are subdivided into two types: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).

According to statistics, approximately 20-45% of Canadians have such condition, but only a low percentage of patients seek help from physicians. and functional dyspepsia accounts for 62.5% of dyspepsia in a population of black African patients, compared to other races.

The exact causes of functional dyspepsia are unidentified. Some researchers suggested that excessive acid secretion, inflammation, food allergies, unhealthy lifestyle choice and long term use of medications may have strong implications in the onset of the syndrome.

Pain, digestive discomforts such as fullness and bloating, excessive burping, nausea, and sometimes vomiting GERD, a sour taste in the mouth are the most common symptoms of functional dyspepsia.

If you experience some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility.

Some researchers suggested that unhealthy dietary habits are one of the major risk factors associated with the onset of FD in the world.

Dr. Ji-Hao Xu, the lead scientist in the assessment of dietary habit in the risk of FD, wrote, "Unhealthy dietary habits were more prevalent in the FD group than in the control groups (75.86% versus 37.50%; p<0.001). FD was found to be associated with irregular mealtime, dining out, fatty food, sweet food, and coffee (p<0.05). The impact of each dietary factor varied with FD subtypes".

And,  "Certain types of dietary habits were positively correlated with the prevalence of FD. FD subtypes showed relatively different associations with dietary factors".

The finding strongly suggested by following a healthy diet pattern, FD may be preventable.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.

On the finding a natural therapeutics for the treatment of functional dyspepsia (FD), researchers compared the efficacy of ginger and artichoke supplementation (SG) versus placebo in the treatment of FD.

The prospective multicentre, double-blind, randomized, placebo-controlled, parallel-group comparison of the supplement and placebo over a period of 4 weeks included 126 FD patients given 2 capsules/day (before lunch and dinner (supplementation/placebo: 65/61).

After 14 days, supplement treatment showed a significant amelioration of FD, compared to placebo.

SG treatment group also showed a significant reduction of nausea, epigastric fullness, epigastric pain, and bloating compared to placebo.

Dr.Giacosa A, the lead scientist wrote, "The association between ginger and artichoke leaf extracts appears safe and efficacious in the treatment of FD and could represent a promising treatment for this disease".

In order to reveal more information about artichoke anti-FD property, researchers assessed the efficacy of artichoke leaf extract (ALE) in the treatment of patients with functional dyspepsia (FD).

The double-blind, randomized controlled trial (RCT) included 247 patients with functional dyspepsia treated with either a commercial ALE preparation (2 x 320 mg plant extract t.d.s.) or a placebo.

ALE improved the overall symptom significantly over the 6 weeks compared to the placebo

Similarly, patients treated with ALE also showed significantly greater improvement in the global quality-of-life scores (NDI) compared to the placebo.

Dr. Holtmann G, the lead scientist after taking into account co and confounders wrote in the final report, "he ALE preparation tested was significantly better than the placebo in alleviating symptoms and improving the disease-specific quality of life in patients with functional dyspepsia".

Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of functional dyspepsia (FD), pending to the confirmation of a larger sample and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial by Giacosa A1, Guido D2, Grassi M2, Riva A3, Morazzoni P3, Bombardelli E3, Perna S4, Faliva MA4, Rondanelli M. (PubMed)
(2) Efficacy of artichoke leaf extract in the treatment of patients with functionaldyspepsia: a six-week placebo-controlled, double-blind, multicentre trial by Holtmann G1, Adam B, Haag S, Collet W, Grünewald E, Windeck T. (PubMed)
(3) Certain Dietary Habits Contribute to the Functional Dyspepsia in South China Rural Area by Xu JH1, Lai Y1, Zhuang LP2, Huang CZ1, Li CQ1, Chen QK1, Yu T1. (PubMed)

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