Ovarian cancer is the medical and chronic condition characterized by irregular cells growth in the tissues found either in at the tail ends of the fallopian tubes or the ovaries.
According to the statistics provided by the American Cancer Society, ovarian cancer is one of the dealy reproductive cancer in women. Every year, the disease causes more deaths than any other cancer of the female reproductive system.
The exact causes of ovarian cancer are not identified. However, epidemiological studies suggested that women who have endometriosis, genetic preposition such as BRCA1 and BRCA2 gene, acquired genetic mutation such as TP53 tumor suppressor gene are susceptible to the substantial risk of the development of the disease.
In seeking a natural product which processes anti-ovarian cancer property, researchers examined the effects of 3,3'-diindolylmethane (DIM) on ovarian cancer cell viability, invasion, and sensitivity to chemotherapy.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) 3,3'-Diindolylmethane suppresses ovarian cancer cell viability and metastasis and enhances chemotherapy sensitivity via STAT3 and Akt signaling in vitro and in vivo by Zou M1, Xu C2, Li H3, Zhang X4, Fan W. (PubMed)
(2) IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in ovarian cancer cells by Zou M1, Zhang X2, Xu C. (PubMed)