Free radicals are highly reactive molecules. Internally, they are produced by our body cell metabolism. Externally, free radical can enter our body from the environment sources, such as the air we breathe, the food we eat and the water we drink.
In other words, free radicals are everywhere. Any chemicals compounds or molecules which process oxygen atom can be free radicals after chemical interaction.
Free radicals have been found epidemiologically to damage the lipid, and protein and induce the alternation of healthy cell DNA.
Out of all damages caused by overexpression of free radicals, some researchers suggested that lipid peroxidation induced by free radical has a strong implication in the pathogenesis of various disorders and diseases.
The liquid is considered one of the healthy food for replacing the use of white sugar and artificial sweetener by many people.
In the urgency to find a natural compound or therapy for the treatment of acute and chronic free radical-mediated diseases, including atherosclerosis, diabetes, and cancer, researchers examined the honey of multi-floral origin, standardized for total antioxidant power and analytically profiled (HPLC-MS) in antioxidants, in a cultured endothelial cell line (EA.hy926) subjected to oxidative stress.
Native honey (1% w/v pH 7.4, 10(6) cells) showed strong activity against lipophilic cumoxyl and cumoperoxyl radicals through several mechanisms, including suppression/prevention of cell damage, complete inhibition of cell membrane oxidation, of intracellular ROS production and recovery of intracellular GSH.
Taken altogether, honey, particular native and Cuban honey may be considered functional remedies for the treatment of acute and chronic free radical-mediated diseases with no side effects, pending to the confirmation of large sample size and multicenter human study.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Radical-scavenging activity, protective effect against lipid peroxidation and mineral contents of monofloral Cuban honeys by Alvarez-Suarez JM1, Giampieri F, Damiani E, Astolfi P, Fattorini D, Regoli F, Quiles JL, Battino M. (PubMed)
(2) Antioxidant and radical scavenging activity of honey in endothelial cell cultures (EA.hy926) by Beretta G1, Orioli M, Facino RM. (PubMed)
(3) Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging by Slemmer JE1, Shacka JJ, Sweeney MI, Weber JT. (PubMed)