Neuro-toxicity is a condition of brain damage caused by exposure to toxic substances.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
In the analysis of natural compound with neuroprotective effect in patients with diabetes, researchers examined the antioxidants richly present in bilberry fruits effects on diabetes-related brain dysfunctions.
In RGC cultures, VMA and all three anthocyanidins protected the brain against SIN-1 (chloride) toxicity, inhibited lipid peroxidation in mouse forebrain homogenates through the antioxidant property and NMDA-induced morphological retinal damage by allowing high levels of calcium ions (Ca2+) to enter the cells.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Effect of feeding with bilberry fruit on the expression pattern of αCaMKII in hippocampal neurons in normal and diabetic rats by Matysek M1, Mozel S1, Szalak R1, Zacharko-Siembida A1, Obszańska K1, Arciszewski MB. (PubMed)
(2) Bilberry and its main constituents have neuroprotective effects against retinalneuronal damage in vitro and in vivo by Matsunaga N1, Imai S, Inokuchi Y, Shimazawa M, Yokota S, Araki Y, Hara H.(PubMed)
(3) Environmental Chemicals and Human Neurotoxicity: Magnitude, Prognosis and Markers by Anetor J. I. 1, Anetor G.O. 2, Iyanda AA1 , Adeniyi FAA. (the University of Ibadan)