Photokeratitis is an uncommon condition induced eye pain caused by exposure to the ultraviolet (UV) rays from either the sun or artificial sources.
24 hours after irradiation, according to the sample collected, corneal epithelium was significantly thicker in mice orally administered with nano-AST than in the others (p < 0.01), with significantly less NF-κB nucleus translocation involved in the induction of proinflammation, and significantly fewer TUNEL cells associated with apoptotic DNA fragmentation.
Dr. Harada F, the lead researcher said, "Oral administration of nano-AST demonstrated a protective effect on UV-induced photokeratitis via antioxidative, anti-inflammatory, and antiapoptotic activity".,
Taken altogether, anthocyanin, a carotenoid, presented in seafood, may be considered a functioning remedy for the treatment of photokeratitis, pending to the validation of larger sample size and multicenter human study.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Protective Effects of Oral Astaxanthin Nanopowder against Ultraviolet-Induced Photokeratitis in Mice by Harada F1,2, Morikawa T1, Lennikov A3,4, Mukwaya A3, Schaupper M3, Uehara O5, Takai R6, Yoshida K1, Sato J1, Horie Y7, Sakaguchi H8, Wu CZ2,9,10, Abiko Y1, Lagali N3, Kitaichi N. (PubMed)
(2) Amelioration of ultraviolet-induced photokeratitis in mice treated with astaxanthin eye drops by Lennikov A1, Kitaichi N, Fukase R, Murata M, Noda K, Ando R, Ohguchi T, Kawakita T, Ohno S, Ishida S. (PubMed)