Arnica may have substantial and sustainable effect in reducing risk, progression, and treatment of leukemia, some scientists suggested.
The results of these report were conducted by numbers of respectable institutes, including the Chonnam National University and Westfälische Wilhelms-Universität and published online on the database of medical literature.
Leukemia is a medical condition characterized by cells growth uncontrollable and disorderly produced by the body's blood-forming tissues, including the bone marrow and the lymphatic system. In most cases, it is the result of abnormal white blood cells, which don't function properly.
The exact causes of leukemia are unknown. However, certain risk factors including smoking, mutation gene inherited from parents such as Down syndrome. blood disorders such as myelodysplastic syndrome are associated with the increased risk of the disease.
Wound healing is a process of repairing after the damage of skin, tissues, organs, etc.
Leukemia is a chronic condition characterized by high numbers of abnormal white blood cells in the bone marrow.
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the investigation of the effect of helenalin, a bioactive chemical compound isolated from Arnica on human promyelocytic leukemia HL-60 cell line, researchers found that application of the compound exerts a significant effect in induced HL-60 cell differentiation through the expression of granulocytes, white blood cells with secretory granules in its cytoplasm, at a concentration-dependent manner.
Additional differentiation also suggested that helenalin induced expression of protein kinase C (PKC) inhibitors without interfering with PKC activity and protein level of PKC beta I and PKC beta II isoforms activities which have been found to promote progression of human cancer.
However, additional data collection on large example size and multi-centers studies performed with human consumption of herbal arnica or its' bioactive sesquiterpene lactones during the course of the disease will be necessary to complete the picture of garlic anti-leukemia possibilities.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Induction of human leukemia HL-60 cell differentiation via a PKC/ERK pathway by helenalin, a pseudoguainolide sesquiterpene lactone by Kim SH1, Oh SM, Kim TS. (PubMed)
(2) Cytotoxic sesquiterpene lactones mediate their death-inducing effect in leukemia T cells by triggering apoptosis by Dirsch VM, Stuppner H, Vollmar AM. (PubMed)