Scientists may have found a beverage which processes the ability to protect the central nervous system against the onset of spinal muscular atrophy, some studies suggested.
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder affected the part of the nervous system that controls voluntary muscle movement due to loss of motor neurons and progressive muscle wasting.
In the investigation to reexamine, the laboratory-based evidence suggest that purified polyphenol compounds such as resveratrol, found naturally in red grapes, epigallocatechin galate from green tea and curcumin from turmeric, might be useful for the treatment of various inherited neuromuscular diseases, including spinal muscular atrophy, researchers at the RJAH Orthopaedic Hospital launched an investigation to evaluate the scientific evidence related to the known molecular effects that these polyphenols have on different models of inherited neuromuscular disease, with particular attention to problems with the validity of in vitro evidence.
Polyphenols, in vitro, exerts a significant effect on cells through metal ion chelation in cell-culture media.
Dr. Fuller HR, the lead author after taking into account co and confounders said, "Polyphenols could be an attractive approach to therapy for the inherited neuromuscular disease, especially since they may be safer to use on young children, compared with some of the other drug candidates".
Taken altogether, green tea purified polyphenols may be considered an adjunct therapy combined with conventional medicine for the treatment of various inherited neuromuscular diseases, including spinal muscular atrophy
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Naturally occurring plant polyphenols as potential therapies for inherited neuromuscular diseases by Fuller HR1, Humphrey EL, Morris GE. (PubMed)
(3) Epigallocatechin-3-gallate protects motor neurons and regulates glutamate level by Yu J1, Jia Y, Guo Y, Chang G, Duan W, Sun M, Li B, Li C.(PubMed)