Wednesday, 31 October 2018

Eggplant, The Veggie Which Normalizes the Blood Cholesterol with No Side Effects

By Kyle J. Norton

Eggplant  may process a significant effect in decreasing the risk and onset of abnormally high blood cholesterol, some scientists suggested

Cholesterol, the waxy substance produced by the liver or intake from the dietary sources plays an important role in the building of the cell walls, producing steroid hormones and promoting the digestive function in food digestion.

However, high levels of blood cholesterol can weaken the arterial wall and block the blood flow in the arteries, leading to the substantially increased the risk of heart diseases and stroke.

The ratio of total cholesterol is 4/1, any numbers that are less than is considered within the healthy range. The lower of the ratio is an indication that you have a higher than normal amount of high-density lipoprotein (HDL), which is essential to remove blood cholesterol from the blood back to the liver, leading to less low-density lipoprotein (LDL) in the initiation of cardiovascular diseases.

The below table Classification of cholesterol levels, provided by Dr.Michael Tanner and Dr. Nate Link the lead author at the New York University School of Medicine and Bellevue Hospital Center New York,
Cholesterol, mmol/L (mg/dL)Classification
<5.17 (<200)Desirable
5.17-6.19 (200-239)Borderline
≥6.20 (≥240)High
<1.00 (<40)Low
≥1.43 (≥60)High
US prevalence (%) of high total cholesterol levels (≥6.21 mmol/L [≥240 mg/dL]) and coronary artery disease (NHANES III: 1988-1991)1
Age, yrHigh cholesterol levelCoronary artery disease

Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.

The plant has been cultivated in southern and eastern Asia since prehistory. It is famous with its deeply purple and the best eggplant can be found from August through October when it is in season.

Chemical constituents of eggplant include sterols (i.e. typical plant sterols, androstane, pregnane and cholestane derivatives, steroidal alkaloids and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin and other Polyphenolic compounds.

In the study to reaffirm the Eggplant (Solanum melongena) consumed extensively in Brazil may have a strong effect in reducing the serum cholesterol researchers at the Instituto de Ciências Biológicas conducted an evaluation to test the plant cholesterol metabolism and hypocholesterolemic effect

In the total of 38 hypercholesterolemic human volunteers ingesting S. melongena infusion for five weeks, 38 hypercholesterolemic subjects were given either S. melongena infusion (N = 19) or placebo (N = 19) participated in two clinical experiments in which the effect of S. melongena infusion was studied with (N = 16) or without (N = 38) dietary orientation.

S. melongena infusion significantly reduced the blood levels of total and LDL cholesterol and of apolipoprotein B.

After dietary orientation, no intra- or intergroup differences were seen for any of the parameters analyzed.

The results suggest that S. melongena infusion had a modest and transitory effect, which was not different from that obtained with standard orientation for dyslipidemia patients (diet and physical activities).

Dried powdered fruits of eggplant (Solanum melongena) was tested in a double-blind placebo-controlled study of the effectiveness of oral Solanum melongena (SM) consisted of 41 hyperlipidemic volunteers allocated to active treatment (n= 21) or placebo (n= 20).

Each volunteer received two capsules containing SM (450 mg) or placebo (450 mg) twice daily and was followed monthly. The dose of SM used corresponds to that given to treat hyperlipidemia in Brazil.

After 3 months, serum total cholesterol, LDL-c, and LDL-c/HDL-c decreased (p<0.05) in the group treated with SM.

Dr. Silva GE, the lead author wrote at the final report of the study, " SM, at least in the form commercialized in Brazil (dried powdered fruits), require further clinical trials before being recommended to treat hyperlipidemia".

Taken altogether, eggplant may be considered a functional food for the prevention and an adjunct therapy for the treatment of high blood cholesterol with no side effects.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension by Kwon YI1, Apostolidis E, Shetty K.(PubMed)
(2) Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects by Guimarães PR1, Galvão AM, Batista CM, Azevedo GS, Oliveira RD, Lamounier RP, Freire N, Barros AM, Sakurai E, Oliveira JP, Vieira EC, Alvarez-Leite JI.(PubMed)
(3) [Absence of hypolipidemic effect of Solanum melongena L. (eggplant) on hyperlipidemic patients].[Article in Portuguese] by Silva GE1, Takahashi MH, Eik Filho W, Albino CC, Tasim GE, Serri Lde A, Assef AH, Cortez DA, Bazotte RB.(PubMed)
(4) Hyperlipidemia: Part 1. Evaluation and dietary management by Michael Tanner1 and Nate Link.(PMC)

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