Herbal Calendula may have a potential effect in reducing risk and treatment of edema, some scientists suggested.
Edema is a condition characterized by an abnormal accumulation of fluid in certain tissues within the body due to injury or inflammation.
The herb has been used in herbal medicine as spasmolytic, spasmogenic, inflammatory effects and to treat abdominal cramps, wound healing, skin diseases, colitis, constipation, etc.
Besides major chemical constituents of triterpenoids, flavonoids, coumarines, quinones, volatile oil,carotenoids and amino acids, the herb also contains loliolide (calendin), calendulin and n-paraffins.
In the study to examine the anti-inflammatory effect of Calendula officinalis flower extract against paw edema, researchers at the Amala Cancer Research Centre, launched an investigation in the paw edema of animals induced by carrageenan and dextran.
Three derivatives of Rings A, D, and E of faradiol, the C(16) benzyl ether 15, the C(30) aldehyde 24, and the C(30) primary alcohol 25 isolated from the herb also showed a significantly improved anti-inflammatory potency.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Phytochemical Constituents and PharmacologicalActivities of Calendula officinalis Linn (Asteraceae): A Review by BP Muley, SS Khadabadi and NB Banarase (Tropical Journal of Pharmaceutical Research)
(2)Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action by Preethi KC, Kuttan G, Kuttan R.(PubMed)
(3) Improved anti-inflammatory activity of three new terpenoids derived, by systematic chemical modifications, from the abundant triterpenes of the flowery plant Calendula officinalis by Neukirch H, D'Ambrosio M, Sosa S, Altinier G, Della Loggia R, Guerriero A.(PubMed)