Thursday, 11 October 2018

Cinnamon, The Natural Heart Disease Inhibitor Remedy, Scientists Reveal

By Kyle J. Norton, Master of Nutrients

A recent study suggested that cinnamon reduces the risk of heart disease through its antioxidant, chemopreventive, anti-inflammatory and immunomodulatory properties.

Heart disease kills more than 2,000 Americans every day and approximately 60 million Americans have heart disease.

Anything that damages the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

There are many causes of heart diseases, depending on general types of defect. However, certain risk factors such as smoking,  high blood pressure, abnormally high levels of triglyceride and cholesterol and abnormally high levels of sugar in your blood due to diabetes or insulin resistance are associated to the increased risk of heart disease.

An unhealthy diet is found to be an important risk factor in coronary heart disease. Foods that increased risks of obesity, high blood pressure, also has a strong impact in elevating the risk of heart disease.

Certain medical conditions such as uncontrolled diabetes and longterm diet with high in saturated and trans fats and salts, refined sugar, processed food and less in fruits and vegetables and fibers can substantially increase the risk of developing heart disease.

Mutated gene inherited from the parents, sedentary lifestyle, excessive alcohol consumption, poor hygiene, and longterm stress is also considered significant risk factors of the disease.

These results suggested that heart disease can be prevented if you people follow a lifelong healthy eating and lifestyle.

Cinnamon is a spice derived from the inner bark of a tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae.

The herb has been used in herbal and traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc.

 In the examine the anti-heart disease of Cinnamomum verum (family Lauraceae), a medicinal global plant that is used daily by people all over the world for reducing blood pressure, plasma glucose, obesity and ameliorating dyslipidemia, a cluster of metabolic syndrome and risk factors of heart disease., researchers launched a search of literature in the databases such as PubMed, Science Direct, Scopus, Web of Science, Google Scholar and Persian Websites.

The keywords search were cinnamon, Cinnamomum, cinnamaldehyde, atherogenic, hypertension, hyperglycemia, insulin resistance, obesity, and dyslipidemia. All studies satisfied the criteria and guidelines are include in the evaluation.

Most studies suggested that cinnamon is a cardiovascular protective agent and has a potential effect in reducing MetS complications due to its anti-diabetic, anti-oxidant, anti-inflammatory and beneficial effects in lipid profile.

Cinnamon also processed various types of antioxidants and activities in increasing the host antioxidant enzymes such as  SOD, GPX, and CAT that leads to the elimination of ROS as well as decreasing lipoperoxidation (LPO) level and decreases the risk of heart disease and mortality.

The National and international dietary recommendations are to eat between five and 10 servings of fruit and vegetables daily to ensure adequate intake of acute and chronic disease-fighting antioxidant nutrients, including heart disease. 

Dr. Hamid Mollazadeh, the lead researchers said, "The antiatherosclerotic effects and preventive vascular diseases of cinnamon resulted from inhibition of vascular smooth muscle cell proliferation through blockade of thromboxane A2 (TXA2) receptors mediated proliferation by cinnamon" and  "Cinnamophilin, a lignin isolated from C. philippinense, inhibited in vitro human platelet aggregation, alongside [3H] inositol monophosphate formation, thromboxane B2 (TXB2) content".

However, in the concerns of antioxidant effects through the intake of individual antioxidant such as supplementation, the Cleveland Clinic in the article wrote, "Vitamin E did not provide any benefit in lowering mortality compared to control treatments, and it did not significantly decrease the risk of cardiovascular death or stroke" and "Beta-carotene led to small but statistically significant increase in all-cause mortality and a slight increase in cardiovascular death".

The joint study led by the North Khorasan University of Medical Sciences, also suggested the use of cinnamon for prevention and treatment of CVD, probably due to its activities in inhibition of metabolic syndrome (MetS), the leading cause of heart diseases.

In support of the above suggestion, some recent studies reaffirm the importance of cinnamon as a spice and maybe a natural remedy to treat cardiovascular diseases.

Furthermore, intake of cinnamon powder also exerted a beneficial effect on glycaemic control in animals and human models, affecting the progression of metabolic alterations in the early stage of cardiovascular events.

Dr. Deng said, "The hypoglycemic effects of cinnamon and .... were demonstrated in most of the trials with some exceptions" and " Future studies with more defined participants, standardized preparation and dose, and improved trial design and size are warranted".

Taken together, cinnamon may be beneficiary for the prevention, management, and treatment of heart disease, but the quantity used of cinnamon should only be prescribed by a herbalist in the prevention of toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) The importance of selected spices in cardiovascular diseases by Kulczyński B1, Gramza-Michałowska A1. (PubMed)
(2) Cinnamon effects on metabolic syndrome: a review based on its mechanisms by Mollazadeh H1, Hosseinzadeh H2.(PubMed)
(3) Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer's disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities by Hamidpour R1, Hamidpour M2, Hamidpour S1, Shahlari M1. (PubMed)
(4) Effect of Cinnamon Tea on Postprandial Glucose Concentration by Bernardo MA1, Silva ML1, Santos E1, Moncada MM1, Brito J1, Proença L1, Singh J2, de Mesquita MF1.(PubMed)
(5) Antioxidants, Vitamin E, Beta Carotene, & Cardiovascular Disease by Cleveland Clinic

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