Thursday, 4 October 2018

Green Tea, The Potent Functional Beverage Which Protects Your Lung Against The Onset of Pneumonia, Medline Studies Find

Kyle J. Norton 

Green tea may have a therapeutic and positive effect in inhibiting the onset of pneumonia, some scientists suggested.

Pneumonia is a lung infection caused by bacteria, viruses, or fungi. The disease may be contagious, as it can spread from person to person, depending to types infectious pathogens.

However, pneumonia induced by fungal passed from the environment to human is not contagious from person to person.

Bacteria Gram-positive cocci. Streptococcus pneumoniae are most causes of community-acquired pneumonia in adults and Haemophilus influenza is the second most common cause of bacterial pneumonia.

Additionally, people who have a weakened immune system, are hospitalized or being on a ventilator. and smoking are most likely to be infected the disease.

Certain chronic medical condition including asthma, chronic obstructive pulmonary disease, structural lung disease, and heart disease are found to associate with the increased risk of pneumonia.

The common symptoms of include chest pain when you breathe or cough, persistent coughing, fatigue. fever, sweating and shaking chills. If you over the age of 50, you may also have the symptoms of confusion or changes in mental awareness'

According to the statistic, the disease affects over approximately 450 million people a year, in all parts of the world.

 Green tea is a precious drink processed numbers of health benefit known to almost everyone in Asia and the Western world.

In the investigation of green tea bioactive polyphenol catechins activity in the inhibition of infectious agents, researchers at the Tohoku University Graduate School of Medicine launched a population-based cohort study, with follow-up from 1995 to 2006, using the database of  National Health Insurance beneficiaries in Japan (19,079 men and 21,493 women aged 40-79 y).

Participants with missing reports of green tea consumption and a history of cancer, myocardial infarction, stroke, and extreme daily energy intake at baseline were excluded.

The comparison of green tea intake and the risk of death in patients with inflammatory pneumonia was analyzed according to the Cox proportional hazards regression analysis.

According to the review, after 12 years of follow up, researchers found that participants who drink <1, 1-2 cups/d, 3-4 and > or =5 cups/d expressed a reduced risk of the hazard of 1, 0.59, 0.55, 0.53, respectively.

These results indicated that green tea intake was associated with the significantly lower risk of death in patients with pneumonia.

Also, the results of the efficacy of green tea increased substantially and linearly to numbers of cup consumed per day. 

Further analysis to confirm the inhibitory effects of tea polyphenols on Chlamydia trachomatis and C. pneumoniae In vitro, researchers at the Saitama Medical School, Iruma conducted an experiment of injection of tea polyphenols, Polyphenon 70S into Chlamydial strains including C. trachomatis D/UW-3/Cx and L(2)/434/Bu, and C. pneumoniae AR-39 and AC-43 strains cultivated in cells and HL cells.

At the final phase of the experiment, researchers indicated that in the pre-inoculation method, application of Polyphenon 70S Completely inhibits both straits without inducing any adverse effects.

However, in the post-inoculation method, injection of Polyphenon 70S at a dose of at 0.5 mg/ml demonstrated no inclusive effect against of C. trachomatis but induced toxicity to HeLa229 cells and HL cells at a concentration of 0.25 mg/ml.

Additional differentiation concluded that application of tea polyphenols may be considered as a potential topical usage. 

Interestingly, in the study to clarify the in vitro effect of EGCG on C. pneumoniae mediated IgE responses by peripheral blood mononuclear cells (PBMC) in asthma by using PBMC from subjects with asthma and non-asthmatic controls incubated with C. pneumoniae and cultured for 10 days ±EGCG (0.5, 5.0, 50 ng/mL), with IgE levels of PBMC from non-asthmatics of <2.0 ng/mL) at baseline scientists showed that application of EGCG (0.5-50 ng/mL) displays a significantly inhibitory effect of PBMC from the asthma patient, by suppressing the IgE production in a dose-dependent manner (10-30%), compared to no EGCG treatment group.

More importantly, injection of green tea EGCG exerted insignificant effect against PBMC from non-asthmatics incubated with C. pneumoniae as the  IgE levels are undetectable (<2.0 ng/mL).

These results suggest that green tea EGCG demonstrated a cell protective activity against bacterial invasion through its cytotoxicity without causing harm to nearby healthy cells.

Taken together, green tea and its bioactive polyphenols may be considered as functional food in amelioration of the risk and treatment of pneumonia. Intake of green tea supplement should be taken with extreme care, as acute liver toxicity was reported in numbers of cases.

However, further data collection on large example size and multi-centers studies performed with human consumption of the beverage during the course of the disease will be necessary to complete the picture of green tea anti-pneumonia possibilities.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) Green tea and death from pneumonia in Japan: the Ohsaki cohort study by Watanabe I1, Kuriyama S, Kakizaki M, Sone T, Ohmori-Matsuda K, Nakaya N, Hozawa A, Tsuji I.(PubMed)
(2) In vitro inhibitory effects of tea polyphenols on the proliferation of Chlamydia trachomatis and Chlamydia pneumoniae by Yamazaki T1, Inoue M, Sasaki N, Hagiwara T, Kishimoto T, Shiga S, Ogawa M, Hara Y, Matsumoto T.(PubMed)
(3) Epigallocatechin gallate suppresses Chlamydia pneumoniae mediated IgE responses in peripheral blood mononuclear cells: a pilot study by Smith-Norowitz TA1, Chotikanatis K, Tam E, Norowitz YM, Joks R, Durkin HG, Hammerschlag MR, Kohlhoff S.(PubMed)
(4) Protective effects of (-)-epigallocatechin-3-gallate against TNF-Ī±-induced lung inflammation via ROS-dependent ICAM-1 inhibition by Lee IT1, Lin CC, Lee CY, Hsieh PW, Yang CM. (PubMed)