Wednesday, 3 October 2018

Black Bean, The Potent Anti Liver Cancer Legume

By Kyle J. Norton(Scholar, Master of Nutrients), all right reserved

People who turn to alternative medicine for treatment of disease in avoidance of adverse effects induced by conventional medicine should be patient.

Compared to herbal medicine; food therapy even takes longer than six months to ease symptoms, depending on the stage of the treatment which directly addresses the cause of disease.

Intake of black bean regularly may have a profound effect in reducing risk and treatment of liver cancer, a renowned institute study proposed.

Liver cancer is a condition of the abnormal growth of the cells in the liver's tissue.

According to statistics approximated 40,710 adults (29,200 men and 11,510 women) in the United States will be diagnosed with primary liver cancer this year.

The exact causes of liver cancer. However, researchers believed that age, gender, excessive use of alcohol, obesity, are ethnicity are associated with the increased risk of liver cancer.

Furthermore, gene mutation such as inherited metabolic diseases is also considered as the major prevalent risk factor of liver cancer onset.

More importantly, certain chronic diseases, such as diabetes, infection by hepatitis virus, liver diseases, including cirrhosis, and non-alcoholic fatty liver disease chemical toxins and long-term use of certain medication such as acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs) aspirin, also have the potential to increased risk of liver cancer.

Besides sharing the general symptoms of cancers, patients with liver cancer also experience symptoms of upper abdominal pain and swelling, yellow discoloration of the skin, jaundice,.... and chalky stool.

If you have some of the above symptoms, please check with your doctor to rule out the possibility.

Black bean, small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongings to the family Fabaceae.

The legume can be bought in most grocery stores all around the year in dried and canned forms.

It is believed that black bean was first domesticated growth in South America.

According to the Stocking Hall, Cornell University, phytochemicals isolated from black beans such as triterpenoids, flavonoids, and other compounds exhibited antiproliferative activities against the HepG2 cells, the human liver cancer cell line.

The efficacy of black bean on the ameliorated growth of liver cancer may be attributed to the presence of some potent antioxidants in the expression of apoptosis.

Additionally, consumption of bean not only played a prominent role of gene expression involved the regulation of gene Hspa8 on reduced risk of liver disease but also addressed the important issue of attenuating hepatic stress or toxicity in the rat model.

In fact, increased beans consumption in rats exhibits changes of the hepatic damage caused by liver toxicity. Dr. Daniell EL, the lead author said, "Dry bean (Phaseolus vulgaris L.) consumption is associated with reduced risk for a number of chronic diseases", such as liver cancer.

More interestingly, dietary bean found to associate to the cholesterol 7α hydroxylase and UDP-glucuronosyltransferase genes increased with a connection to the development of liver cancer, in a dose-dependent manner.

These findings suggested that dietary black(dried) bean may have a potential effect in reducing risk and treatment of liver cancer through antioxidant activity and regulated genes involved early onset of the disease.

However, further data collection on large example size and multi-centers studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of black bean anti-liver cancer possibilities.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Phytochemicals of black bean seed coats: isolation, structure elucidation, and their antiproliferative and antioxidative activities by Dong M1, He X, Liu RH. (PubMed)
(2) Dietary dry bean effects on hepatic expression of stress and toxicity-related genes in rats by Daniell EL1, Ryan EP, Brick MA, Thompson HJ. (PubMed)

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