A. Combined Contraceptive Injections
1. Combined contraceptive injection containing both synthesis estrogen and progesterone works similar to the pill and mostly is given through the muscle of the arm for every 28 days to provide maximum protection.
2. Symptoms and Risks
a. Blood clots
All hormonal methods of birth control pose a threat to normal blood flow, the combined contraceptive injection is no exception, it increases the risk of of blood clots in your legs or on the lung caused by estrogen in the injrction that makes your blood thicker in the veins.
Woman who injected with the combined contraceptive injection increases the risk of stroke caused by blockage of blood flow to the brain as resulting of high level of estrogen in the injection that reduces the oxygen transportation as the blood getting thicker.
c. Heart disease
Similar to the stroke, as our blood get thicker, our heart has to pump harder to provide oxygen for our body cells need causing hypertension. If our heart has to work that hard for a prolong period of time because of long term use of the combined contraceptive injection, it will be damaged causing heart disease.
d. Skin pigment
Some woman may experience increasing of pigmentation of skin that shows up in patchy and light brown area caused by estrogen in the combined contraceptive injection.
e. Mood swing
Some women may experience mood swing due to synthesis combined injection caused by significant changes in your hormone levels affecting the chemicals that regulate mood such as level of estrogen and progesterone.
f. Bleeding and spotting
Bleeding and spotting when you are not scheduled to bleed and spotting, are very common in the use of combined contraceptive injection, because your body has to take time to adjust to the change of hormone level.
Some women after coming off the Combined contraceptive injection and hope to get pregnant, they may be disappointed. Not only the effects of combined contraceptive injection may be needed sometime to wire off, our body may never be able to adjust, causing lost of period permanently.
h. Increase the size of fibroids
Combined contraceptive injection contains estrogen which promotes the growth of fibroids. If you have fibroids and you want to get the injection, you should talk to your doctor first.
3. The advantages of Combined contraceptive injection
a) Control unwanted pregnancy
Combined contraceptive injection helps to protect woman against any unwanted pregnancy, because it stops or reduces period.
b) Control menstrual cramps
It helps to inhibit the over production of prostaglandins which cause the muscles spam contraction in the abdomen, resulting of less period pain and period flow.
c) Reducing the rate of reproductive organ diseases
Study shows that combined contraceptive Injections reduce the rate of ovarian and endometrial cancer, benign breast disease, benign ovarian cysts, pelvic inflammatory disease, because of stopping or reducing of period blood flow.
d) Shinking endometriosis
Endometrial implants, adhesion or cysts no longer active, because there are no substance to activate the menstrual cycle.
Since anemia is a disease of iron deficiency, intake of the pill stops or reduces the period blood, there are less iron needed to be produced by the liver or other organs
helps reduce the rate of ovarian and endometrial cancer, benign breast disease, benign ovarian cysts, pelvic inflammatory disease, because of stopping or reducing of period blood flow.
Since anemia is a disease of iron deficiency, combined contraceptive injection stops or reduces the period blood, there are less iron needed to be produced by the liver or other organs
The disadvantage of Combined Contraceptive Injections
a) Bleeding and spotting
Bleeding and spotting is normal for the first six months for women who startcombined contraceptive injection because our body needs time to adjust to the new medication.
b) Lost interest in sex
Women who injected with combined contraceptive injection are in danger of permanently lost their interest in sex because the injection inhibits testosterone, the hormone that drives sexual desire even after if it is stop.
c) Chloasma or melasma
It is caused by hormonal changes due to combined contraceptive injection.
d) Nutritional deficiency
Combined contraceptive injection causes vitamin and mineral imbalances or deficiencies. It depletes magnesium for healthy heart, coenzyme Q10 for healthy heart muscles, folic acid for preventing cervical abnormalities, vitamin B6, B2, B3, zinc, etc. for reducing the period blood.
e. Growth of fibroids
Fibroid starts from a single cell that grows abnormally. Fibroid occurs mostly in women after puberty and shrink after menopause. Growth of fibroid is caused high level of estrogen and progesterone. The combined contraceptive injection promotes the level of both hormones resulting of increase the risk of growth of fibroid.
f. Recurrent of menstrual symptoms
Some women stop taking the combined contraceptive injection may see all the menstrual symptoms coming back.
g. Blood clots
Combined contraceptive injection causes the blood getting thicker resulting in blood clots in the small vessels in the leg and the lung.
h. Stroke and heart diseases
Study shows that women who have higher natural estrogen levels may have a higher risk of stroke and heart diseases caused by estrogen in the combined contraceptive injection that blocks hormonal actions in some parts of the body, while increasing its effects in the heart and others
i. Hormonal imbalance
The combined contraceptive injection may influence the imbalance hormones of estrogen and progesterone due to our body needs time to adjust.
j. Depression and mood swing
The combined contraceptive injection, at the beginning may cause abnormal fluctuations in estrogen and progesterone, elevating both physical and psychological stress, eventually resulting in both depression and mood swing.
k. Prolong used of combined contraceptive injection may cause loss of period in some women. Some women may take months or year to get their period back. resulting of infertility.
B. Progestogins contraceptive injection
1. Depo Provera Shot
Depo Provera Shot is a type of synthesis progestogins injective medicine manufactured by Pfizer, in US. It is similar to the protestogens in contraceptive pill used to thicken the uterine mucus to prevent the sperm from passing through and suppressing ovulation. Depo Provera shot must be given every 3 months to provide a maximum protection.
2. Noristerat infection
Noristerat infection is a type of synthesis progestogins hormone, injected through the muscle of the button, the medicine will present itself in the bloodstream to provide birth control for upto 2 months. Noridterat has not been approved in US, but widely used in the Euro or some other parts of the world.
a. Breast tenderness
Due to the absence of estrogen and high amount of progesterone hormone in the body, that can cause breast tenderness.
b. Weight gain
Since the infection creates a pregnancy state, it can cause weight gain such as you are pregnant.
c. Psychaitric Disorders
There are reported that women who have taken the progestogins contraceptive injection can increase the risk of developing of depression, anxiety, personality disorders, irritability , etc.
d. Menstrual Changes
Progestogins contraceptive injection can change your period., you may experience irregular bleeding, period with shorter and lighter bleeding, etc.
e. Digestive Problems
The progestogins contraceptive injection can also cause heartburn, diarrhea or vomiting due to persistent amount of synthesis progesterone in the body.
4. Advantages of progestogins injection
a. sexual Interruption
Women who take the progestogins contraceptive injection are in danger of permanently lost their interest in sex because the synthesis progesterone inhibits testosterone, the hormone that drives sexual desire.
b. It is an ideal for breast feeding women
Crossing over synthesis progesterone does not affect the baby health.
c. It is ideal for women who can not take the combined contraceptive injection as it can cross into breast milk, causing harmful to the health of baby, while breastfeeding.
d. It may helps to release premenstrual symptoms and painful period
Since the combined contraceptive injection decrease the levels of FSH that prevents the increase in estradiol levels, leading to inhibition of follicular development and the absence of a LH surge, thus preventing ovulation.
f. You are protected against infectious reproductive diseases
Since combined contraceptive injection affects the mucus around the cervix, making it harder for sperm to enter the uterus,thus reducing the risk of sexual transmitting disease such as HPV.
5. The disadvantage of combined contraceptive injection
a. Ovarian cyst
Increased risk of functional ovarian cyst due to suppress of ovulation as a result of inhibition of follicular development and the absence of a LH surge.
b. Etopic pregancy
An ectopic pregnancy occurs when a fertilized egg implanted somewhere else other than inside the uterus. The low levels of estrogen increase the risk of its function in transporting the fertilized egg from the Fallopain tuble to the uterus.
c. Increased risk of breast cancer
In 2 studies of use of estrogen, progestins, and progesterone from France, researchers found that sharp contrast between natural progesterone and the use of progestins. In conjunction with a transdermal estradiol gel, there was no increase in rates of breast cancer in the women using natural progesterone. Additionally, a recent review of progestins, progesterone, and breast cancer risk looked at over 100 references and found that only the synthetic progestins, particularly when given continuously, increased breast cancer risk.
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