In the study to evaluate dietary interventions regarding their safety and metabolic
effects, indicated that these high-fat diets have been shown to be safe in the short
term; however, their long-term safety has not been established. With
respect to insulin sensitivity, diets enriched in saturated fats can
induce insulin resistance, whereas fat substitution with monounsaturated
fats can enhance insulin sensitivity. On the other hand, high-fiber,
high-carbohydrate diets comprised of foods with low caloric density can
similarly be used for effective weight
reduction and to ameliorate insulin resistance. Although some data
suggest that low-glycemic index diets are most advantageous in this
regard, these effects may have more to do with increments in dietary
fiber than differences in available carbohydrates. Popular
low-carbohydrate, high-fat diets are being fervently embraced as an
alternative to challenging modifications in lifestyle and intentional
calorie reduction. Current data do not support such unbridled enthusiasm
for these diets, particularly in relationship to high-fiber,
high-carbohydrate diets emphasizing intake of fresh vegetables and
fruits(1).
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(1) "Diet, insulin resistance, and obesity: zoning in on data for Atkins dieters living in South Beach" by
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