Changes in Dermal Histomorphology Following Surgical Weight Loss Versus Diet-Induced Weight Loss in the Morbidly Obese Patient.

In the investigation of Between July 2008 and December 2010, 30 consecutive patients with significant weight loss (17 surgical, 13 nonsurgical) underwent a panniculectomy (n = 15), abdominoplasty (n = 13), and lower body lift (n = 2), with an average age of 48.3 ± 11.10 years and a body mass index of 39.23 ± 13.65 kg/m conducted by Duke University Medical Center, found that Blinded histologic evaluation revealed a trend toward normal elastic fiber appearance (P = 0.255), increased wound complications (P = 0.546), and mild inflammation (P = 0.462) in the surgical group. Analysis of dermal histomorphology correlating with wound complications was not statistically significant at follow-up (4.76 ± 5.55 months). Interestingly, there was a persistent inflammatory component in both groups when compared with age-matched controls

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(1) "Changes in Dermal Histomorphology Following Surgical Weight Loss Versus Diet-Induced Weight Loss in the Morbidly Obese Patient". by Fearmonti RM, Blanton M, Bond JE, Pestana IA, Selim MA, Erdmann D.