Phytochemical Sinigrin may be used as a natural ingredient for the treatment of bladder cancer, according to studies.
Bladder cancer is a medical condition characterized by cell growth uncontrollably in the bladder tissue, due to the alternation of DNA.
Most cases of bladder cancer start in the cells of the inner lining of the bladder tissue. At the early, due to the small size and on the surface of the inner lining, most patients do not experience any symptoms.
However, at the advanced stage, the larger size tumor may press on the nearby blood vessels and nerve cells, leading to the symptoms of burning sensation, blood in the urine, abnormal urinary activity, particularly, severe abdominal pain and back pain on one side of the body.
If you experience some of the symptoms, please check with your doctor to rule out the possibility of bladder cancer.
Also, at this stage, the cancer cells can also travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.
Epidemiologically, smoking, the increased in age, chronic bladder inflammation and long-term exposure to toxic chemicals are the most prevalent risk factors for bladder cancer.
Recently, some researchers start to question the risk of bladder cancer in the obese population.
Dr. Qin Q. wrote, "A total of 11 cohort studies were included in our meta-analysis, which showed that obesity was associated with an increased risk for bladder cancer in all subjects (RR=1.10, 95% CI=1.06-1.16; p=0.215 for heterogeneity; I2=24.0%). Among the 9 studies that controlled for cigarette smoking, the pooled RR was 1.09 (95% CI 1.01-1.17; p=0.131 for heterogeneity; I2=35.9%)"
Sinigrin is a phytochemical glucosinolate, belongs to the family of glucosides found abundantly in Brussels sprouts, broccoli, the seeds of black mustard, etc.
Researchers on finding a bioactive compound for the treatment of bladder cancer examined the effects of AITC-rich mustard seed powder (MSP-1) with AITC stably stored as its glucosinolate precursor (sinigrin) in MSP-1.
The finding strongly suggested that MSP-1 exhibited the AITC in the inhibition of bladder cancer development and progression.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion by Bhattacharya A1, Li Y, Wade KL, Paonessa JD, Fahey JW, Zhang Y. (PubMed)
(2) Selective induction of phase II enzymes in the urinary bladder of rats by allyl isothiocyanate, a compound derived from Brassica vegetables by Munday R1, Munday CM. (PubMed)
(3) Obesity and risk of bladder cancer: a meta-analysis of cohort studies by Qin Q1, Xu X, Wang X, Zheng XY. (PubMed)