Thursday, 1 November 2018

Green Tea, A Potential Healthy and Longevity Functional Food, Scientists Find

By Kyle J. Norton

Regular and daily moderate green tea intake may have a potential effect in increasing the lifespan in human, some scientists suggested.

Some researchers suggested that human longevity without health issue can be achieved through a healthy diet and lifestyle.

Dr. Small GW, the lead author in the study "A short-term healthy lifestyle program combining mental and physical exercise, stress reduction, and healthy diet was associated with significant effects on cognitive function and brain metabolism. Reduced resting activity in the left dorsolateral prefrontal cortex may reflect the greater cognitive efficiency of a brain region involved in working memory".

Would these results be enough for a person to live longer and healthier?

Eating the right foods can lead to a longer, healthier life. Some researchers recommended the following diet for the elderly to liver longevity without some major health issues.
* A basic heart-healthy diet including fruits and vegetables, whole grains, low-fat dairy products like yogurt and cheese, skinless poultry, lots of fish nuts and beans and non-tropical vegetable oils can help to control your weight, because more than a third of people 65 and older are obese, the major cause of diabetes, some cancers, and heart disease.

* A  basic brain-healthy diet including lean meats, deep-sea fish, skim milk products and some whole grain cereals that reduces risk neurodegenerative disease can improve the memory.

* A basic protein diet to build the muscle diet including low-fat or fat-free yogurt, cheese, milk, lean meats, fish, other seafood, and beans.

* A basic diet including calcium and vitamin D in fortified foods, fish like salmon, and dairy products. to build the bone.

In the study to reaffirm the effect of green tea in increasing lifespan in various experimental animal models, researchers at the University of California Irvine launched an investigation to examine whether green tea acts to increase the lifespan of the fruit fly by modulating iron regulators, specifically, mitoferrin, a mitochondrial iron transporter, and transferrin, found in the hemolymph of flies

Application of green tea increased the lifespan of transferrin mutant lifespan but not the mitoferrin mutants and fertility, compared to the increased male fly lifespan and reduced male fertility in the non-mutant group.

These results suggested that green tea may act to increase the lifespan of Drosophila in part by the regulation of mitoferrin and reduction of mitochondrial iron.

Continued to the above investigation, researchers found that the lifespan extension properties of green tea were only observed in the presence of females which alludes to a reproductive (or mating) dependent mechanism.

Furthermore, the application of green tea exerted a strong and negatively impact on male fertility as shown by a reduced number of offspring produced and increased mating latency

These correlations suggested that green tea extends the lifespan of male flies by inhibiting reproductive potential, possibly by limiting iron uptake.

Researchers at the final report indicated green tea may have a profound effect in increasing lifespan but a negative effect on reproductive fitness in humans.

Moreover, in the study of a standardized epigallocatechin-3-gallate (EGCG) rich green tea extract (comprising > 90% EGCG) effects on fitness and lifespan as well as parameters of glucose metabolism and energy homeostasis in the fruit fly, Drosophila melanogaster, researchers found that
* The application of the green tea extract demonstrates a significant increase in the mean lifespan (+ 3.3 days) and the 50% survival (+ 4.3 days) as well as improved fitness

* These effects went along an increased expression of Spargel, the homolog of mammalian PGC1╬▒ whose dysfunction is associated with accelerated aging, decreased mobility and decreased lifespan.

* Treatment with the green tea extract decreased glucose concentrations.

Dr. Wagner AE, the lead scientist said, "a decrease in glucose metabolism in connection with an upregulated expression of Spargel contribute to the better fitness and the extended lifespan in EGCG-treated flies".

Taken all together, green tea may have a profound effect in increasing lifespan in human, depending on the confirmation of further data collection from the large example size and multi-center studies.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Green tea polyphenols require the mitochondrial iron transporter, mitoferrin, for lifespan extension in Drosophila melanogaster by Lopez TE1, Pham HM1, Nguyen BV1, Tahmasian Y1, Ramsden S1, Coskun V1, Schriner SE1, Jafari M. (PubMed)
(2) Green tea polyphenols extend the lifespan of male drosophila melanogaster while impairing reproductive fitness by Lopez T1, Schriner SE, Okoro M, Lu D, Chiang BT, Huey J, Jafari M.(PubMed)
(3) Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster by Wagner AE1, Piegholdt S1, Rabe D1, Baenas N1,2, Schloesser A1, Eggersdorfer M3, Stocker A4, Rimbach G. (PubMed)
(4) Effects of a 14-day healthy longevity lifestyle program on cognition and brain function by Small GW1, Silverman DH, Siddarth P, Ercoli LM, Miller KJ, Lavretsky H, Wright BC, Bookheimer SY, Barrio JR, Phelps ME. (PubMed)
(5) Foods for a Strong Heart, Brain, and Bones By John Donovan

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