Extremely low carbohydrate/high protein diets are popular methods and
well known of weight loss, but compliance to the diet program is poor .
In the evaluation of that six patients with type 2 diabetes (five women
and one man) were randomly assigned to the high-protein diet (40%
carbohydrate, 30% protein, 30% fat) and six patients (four women and two
men) to the high-carbohydrate diet (55% carbohydrate, 15% protein, 30%
fat). All patients returned to the General Clinical Research Center
weekly for monitoring of food records; dietary compliance; and
measurements of body weight, blood pressure, and blood glucose. After 8
weeks on these diets, conducted by Drexel University (1). Scientists
filed the result of that the high-carbohydrate and high-protein groups
lost weight (-2.2+/-0.9 kg, -2.5+/-1.6 kg, respectively, P <.05) and
the difference between the groups was not significant (P =.9). In the
high-carbohydrate group, hemoglobin A1c decreased (from 8.2% to 6.9%, P
<.03), fasting plasma glucose decreased (from 8.8 to 7.2 mmol/L, P
<.02), and insulin sensitivity increased (from 12.8 to 17.2
micromol/kg/min, P <.03). No significant changes in these parameters
occurred in the high-protein group, instead systolic and diastolic blood
pressures decreased (-10.5+/-2.3 mm Hg, P =.003 and -18+/-9.0 mm Hg, P
<.05, respectively). After 2 months on these hypocaloric diets, each
diet had either no or minimal effects on lipid levels (total
cholesterol, low-density lipoprotein, high-density lipoprotein), renal
(blood urea nitrogen, serum creatinine), or hepatic function (aspartate
aminotransferase, alanine aminotransferase, bilirubin).
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(1)
"Effect of high protein vs high carbohydrate intake on insulin
sensitivity, body weight, hemoglobin A1c, and blood pressure in patients
with type 2 diabetes mellitus"Sargrad KR, Homko C, Mozzoli M, Boden G, Posted in PubMed
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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