Wednesday, 11 December 2013

Hyperthyroidism in Pregnancy - Diagnosis and Symptoms

Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones.
Hyperthyroidism during pregnancy mostly happens to younger women and usually is over looked due to the production of hormone HCG (human chorionic gonadotropin) in the first 12 weeks of pregnancy. It is very important that hyperthyroidism is controlled after the 12 weeks of pregnancy, if left untreated, it can increase the risk of miscarriage or birth defect.
Diagnosis of Thyroxine binding globulin (TBG)
Test of Thyroxine binding globulin (TBG) is always important for pregnancy with hyperthyroidism, unfortunately, because of the increasing of the level of thyroid binding globulin (TBG) during pregnancy, the interpretation of the T4 value may be difficult as others factors such as estrogen levels, corticosteroid levels, liver failure and symptoms must be also taken into consideration, according to the study of Interpretation of in-vitro thyroid function tests during pregnancy by Smith SC, Bold AM. Therefore, the test must be focused into the calculation of the free thyroxine index (FTI) or a measurement of the free thyroxine (FT4)
1. Thyrotoxicosis
It is defined as a toxic condition resulting from excessive amounts of thyroid hormones in the body, as that occurring in hyperthyroidism. In pregnancy, if the problem is left untreated, it can may lead to serious consequences, such as Miscarriage, Preterm labor, intrauterine growth
retardation and neonatal thyrotoxicosis and other complications, etc.

2. Transient hyperthyroidism
If the problem is caused by short-term hyperthyroidism due to over active of the thyroid gland as a result of pregnancy, the symptom will go away after 12 weeks of pregnancy. In serve case, antithyroid drugs may be necessary.

1. Weakness
2. Nervousness
3. Heat intolerance
4. Nausea and vomiting
5. Hyperorexia
6. Palpitations
7. lack of concentration
8. Insomnia
9. Breathlessness
10. Increased bowel movements
11. Etc.
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