Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones.
Hyperthyroidism during pregnancy
mostly happens to younger women and usually is over looked due to the
production of hormone HCG (human chorionic gonadotropin) in the first 12
weeks of pregnancy. It is very important that hyperthyroidism is
controlled after the 12 weeks of pregnancy, if left untreated, it can
increase the risk of miscarriage or birth defect.
Diagnosis of Thyroxine binding globulin (TBG)
Test
of Thyroxine binding globulin (TBG) is always important for pregnancy
with hyperthyroidism, unfortunately, because of the increasing of the
level of thyroid binding globulin (TBG) during pregnancy, the
interpretation of the T4 value may be difficult as others factors such
as estrogen levels, corticosteroid levels, liver failure and symptoms
must be also taken into consideration, according to the study of
Interpretation of in-vitro thyroid function tests during pregnancy by
Smith SC, Bold AM. Therefore, the test must be focused into the
calculation of the free thyroxine index (FTI) or a measurement of the
free thyroxine (FT4)
1. Thyrotoxicosis
It is defined as a toxic
condition resulting from excessive amounts of thyroid hormones in the
body, as that occurring in hyperthyroidism. In pregnancy, if the problem
is left untreated, it can may lead to serious consequences, such as
Miscarriage, Preterm labor, intrauterine growth
retardation and neonatal thyrotoxicosis and other complications, etc.
2. Transient hyperthyroidism
If
the problem is caused by short-term hyperthyroidism due to over active
of the thyroid gland as a result of pregnancy, the symptom will go away
after 12 weeks of pregnancy. In serve case, antithyroid drugs may be
necessary.
Symptoms
1. Weakness
2. Nervousness
3. Heat intolerance
4. Nausea and vomiting
5. Hyperorexia
6. Palpitations
7. lack of concentration
8. Insomnia
9. Breathlessness
10. Increased bowel movements
11. Etc.
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