Lycopene the Best Anti Cardiovascular Disease Phytochemical

By Kyle J. Norton

Cardiovascular disease (CVD) is a group of diseases associated with blood vessels and heart muscle. Depending on the location of heart muscle damage or the blood vessel blockage, CVD can be a coronary artery disease caused by the hardening of the arteries that interfere with the blood flow to the heart.

Heart failure, a major health problem associated with the reduced function of the heart, is a leading cause of hospitalization in people older than age 65. Believe it or not, more than 6.5 million Americans are living with the condition of heart failure.

According to the statistics provided by the CDC, every year, heart disease causes the death of 610,000 people in the US. More precisely, 1 in every 4 deaths in the US  every year are caused by heart disease.

Furthermore, every year about 735,000 Americans has a heart attack including the first attack of 525,000 patients.

The exact causes of cardiovascular disease are not cleared. However, epidemiologically family history, age ethnicity, gender, medical conditions such as cholesterol high blood pressure and diabetes has been found in most patients with CVD.

Some researchers in the examined the correlation between a high-fat diet and cardiovascular disease in obese patients suggested that the promotion of a high-fat diet over the past few decades may be one major culprit that causes the onset of CVD.

Dr. Jane E Freedman wrote, " According to the National Center for Health Statistics (1999), 61% of adults in the U.S. are overweight (body mass index [BMI] 25 to 29.9 kg/m2), and 26% are obese (BMI ≥30 kg/m2). Elevated BMI, particularly caused by abdominal or upper-body obesity, has been associated with diseases and metabolic abnormalities including hyperinsulinemia, insulin resistance, type 2 diabetes, hypertension, dyslipidemia, and coronary heart disease.".

And, " clearly established diseases associated with high-fat or high-calorie diets can be offset by the use of nutritional supplements. Although these findings beckon us to draw broader implications, even if proven true in larger studies, it is doubtful that this will lead to a recommendation of high-calorie, high-fat diets".

Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

On finding a natural compound for the prevention of cardiovascular disease, researchers examined the effect of lycopene by a meta-analysis.

According to the 14 studies identified by the search in the medical literature of the database of Pubmed, Embase, and Web of Science from inception to October 2016,

* Lycopene exerted a significant inverse association with a pooled risk ratio (RR) of 0.83 in the risk of CVD.

* Furthermore, dietary lycopene intake was statistically significant in the reduction of risk of coronary heart disease (CHD) with an RR of 0.87 and stroke with an RR of 0.83.

* Lycopene biomarker concentrations were also inversely associated with the risk CVD.

Based on the findings, researchers wrote in the final report, "Higher lycopene exposure is inversely associated with a lower risk of CVD".

Taken altogether, lycopene found in tomato may be considered supplements for the prevention and treatment of CVD, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Lycopene Deficiency in Ageing and Cardiovascular Disease by Petyaev IM. (PubMed)
(2) Lycopene and risk of cardiovascular diseases: A meta-analysis of observational studies by Song B1, Liu K1, Gao Y1, Zhao L1, Fang H1, Li Y1, Pei L1, Xu Y. (PubMed)
(2) High-fat diets and cardiovascular disease. Are nutritional supplements useful? by Jane E Freedman. (JACC Journals)