Thursday, 11 July 2019

Whole Food Ginger Speeds Up the Recovery From Sore Throat (Pharyngitis)

By Kyle J. Norton

Pharyngitis or a sore throat is a condition characterized by the inflammation of the pharynx.

The pharynx. is membrane-lined cavity behind the nose and mouth, connecting to the tubes to the stomach and the lungs.

Most cases of a sore throat are associated with other symptoms such as running nose and abdominal pain,  a cold, influenza caused by a viral infection.

However, group A streptococcus has been found to cause strep throat, which can be treated by antibiotics.

Although it is not common, some cases of a sore throat also are caused by scratchiness in the throat and in people with difficulty swallowing due to reduced circular and longitudinal muscles occurred in the walls of the pharynx.

The time to recover from a sore throat is totally depending on the underlying causes. Most cases of a sore throat can be recovered within 1 week, depending on each individual health status.

Conventionally, treatment of a sore throat is to reduce pain with over accouter medicines and let the condition to run its course.

Some researchers suggested that for a speedy recovery from the viral infection-induced sore throat, patients should drink plenty of fluids to prevent dehydration,  eat warm broth gargling with warm salt water and use a humidifier during the course of the condition.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Researchers on finding a natural compound for the treatment of pharyngitis, an inflammatory condition of the pharynx and associated structures commonly caused by the Group A streptococci (GAS) examined the anti-inflammatory activity of phytochemical-rich extracts prepared from 12 herbal plants using human tonsil epithelial cells (HTonEpiC) in vitro.

The study included HTonEpiC induced by a mixture of lipoteichoic acid (LTA) and peptidoglycan (PGN) (10 µg/mL; bacterial antigens) for 4 h and then exposed to ethanol extracts (EE) or aqueous extracts (AE) including the composition of danshen root, clove, ginger, and echinacea for 20 h.

The extracts exhibited a broad range of reduction of proteins and antimicrobial peptides associated with inflammatory production, including interleukin-8 (IL-8), human beta-defensin-2 (HBD-2).

Further analysis also suggested that both EE and AE of clove, ginger, and Echinacea flower and EE from danshen root significantly inhibited the pro-inflammatory cytokine production.
Dr. Wijesundara NM, the lead scientist, after taking into account of co and confounders, wrote, "The most efficacious extracts from the danshen root, clove, ginger and echinacea flowers have potential to be used as natural sources for developing phytotherapeutic products in the management of painful inflammation due to streptococcal pharyngitis".

Moreover, in order to reveal more information ginger anti-inflammatory activity, researchers evaluated the essential oils (EOs) extracted from oregano, sage, cloves, and ginger for the phytochemical profile, antibacterial, and anti-biofilm activities against Streptococcus pyogenes. 

The microscopic visualization of biofilms treated with EOs have shown morphological and density changes compared to the untreated control.

Compared to the efficacy of oregano, sage in the anti-biofilm agent with dual actions, ginger exerted insignificant activity against antibacterial, and anti-biofilm activities against Streptococcus pyogenes.

Base on the results, ginger may be used combined with other herbal medicine for the treatment of pharyngitis, pending to the confirmation of large sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

(1) Phytochemical-rich medicinal plant extracts suppress bacterial antigens-induced inflammation in human tonsil epithelial cells by Wijesundara NM1, Sekhon-Loodu S1, Rupasinghe HV. (PubMed)
(2) Essential oils from Origanum vulgare and Salvia officinalis exhibit antibacterial and anti-biofilm activities against Streptococcus pyogenes by Wijesundara NM1, Rupasinghe HPV. (PubMed)

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