Most cases of skin cancer in the US are associated with prolong-period of sun exposure. In other words, UV rays that damage the skin have been the main culprit that causes the onset of skin cancer.
Believe it or not, according to the statistics, skin cancer is the most common cancer in the US. one in five Americans will develop skin cancer in their lifetime.
Every day, approximately 9,500 people in the U.S. are diagnosed with skin cancer due to a misunderstanding of the health benefits and risk of sun and tanning exposure.
It is the most common type of skin cancer associated with the abnormal growth of the cells in the lowest layer of the epidermis. Cancer rarely spread and kill but can cause significant destruction and disfigurement to the affected skin area, accounting for more than 90% of all skin cancer in the U.S.
* Squamous cell cancer
It arises from the uncontrolled multiplication of transformed malignant cells in the middle layer of the epidermis.
Melanoma is less common compared to other skin cancer caused by the malignancy of melanocytes, the cell produced dark pigment for your skin.
In the urgency to find a natural ingredient for the treatment of skin cancer, researchers examined the bromelain (BL) effect in the form of nanoparticles (NPs) based delivery systems on skin cancer cells.
The formulated NPs with a mean particle size of 130.4 ± 8.81 nm exhibited sustained release of BL by observation of the analysis.
According to the tested assays, BL loaded poly (lactic-co-glycolic acid) NPs enhanced anti-tumor effects compared to free BL.
Furthermore, administration of NPs also exerted a significant effect on reduced the percent mortality rate and the average tumor volume.
More precisely, NPs demonstrated anti-cancer cell efficacy was attributed to its capability in modulating the expression of pro-apoptotic (P53, Bax) and anti-apoptotic (Bcl2) proteins.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(2) Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway by Bhui K1, Prasad S, George J, Shukla Y. (PubMed)