Herbal Ginger, the Best for the Prevention and Treatment of Hypothermia

By Kyle J. Norton


Hypothermia is a medical condition caused by the loss of heat faster than it can produce heat by the body.

In other words, hypothermia occurs if the body temperature is falling below 95 F (35 C) compared to the normal body temperature of 98.6 F (37 C).

Most cases of hypothermia is a medical emergency as the falling body temperature can lead reduce the function of the heart, nervous system and other organs.

Exposure to cold weather without proper clothing and homeless people in the cold Winter day are the most common cause of hypothermia in Canada.

According to the statistics from the US government, approximately 67% of hypothermia-related deaths were among males. Between 1999 to 2011, there is a total of 16,911 deaths with an average of 1,301 per year associated with exposure to excessive natural cold.

Symptoms of hypothermia are shaking slightly and uncontrollably, lack of coordination, sleepiness, confuse, particularly bright red skin. If you see someone in this condition in the very cold day, please call 911, as this person does not know that he/she has hypothermia.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

With an aim to find a natural compound or whole food for the treatment of hypothermia, researchers examined the anti-hypothermic action of ginger extract (GE) by employing a solid dispersion (SD) (GE/SD) prepared in terms of physicochemical and pharmacokinetic properties.

GE/SD improved dissolution behavior of the major active ingredients in GE for the treatment of the condition.

In other words, GE/SD enhanced the properties of 6-gingerol (6G) and 8-gingerol (8G), against hypothermia with levels of dissolution 12- and 31-fold higher than that of GE, respectively.

However, 6G and 8G were slightly degraded in compared to the GE.

Oral administration of GE (300 mg/kg) and GE/SD (100 mg of GE/kg), the relative bioavailabilities of 6G and 8G in GE/SD were 5.0- and 5.8-fold higher than those in GE, respectively.

The efficacy of GE/SD (30 mg of GE/kg) inhibited ethanol-evoked hypothermia was attributed to the improved oral absorption of 6G and 8G.

Furthermore, in order to reveal more information about GE activity in removing chills caused by common cold and to warm body, researchers the anti hypothermic effect of acetone extract of ginger at 100 mg/kg p.o.

Oral administration of acetone extract of ginger at 100 mg/kg p.o. significantly inhibited serotonin (5-HT) induced hypothermia in tested subjects.

Additional differentiation suggested that [6]-shogaol obtained from fraction 2-2, at 10 mg/kg p.o.was found to potentiate the effect of the acetone extract against the onset of hypothermia.

Take all together, ginger may be considered a functional alternative for the prevention and treatment of hypothermia with no side effects, pending to the confirmation of large sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Ginger Extract-Loaded Solid Dispersion System with Enhanced Oral Absorption and Antihypothermic Action by Sato H1, Ogino M1, Yakushiji K1, Suzuki H1, Shiokawa KI2, Kikuchi H2, Seto Y1, Onoue S1. (PubMed)
(2) [The effect of ginger on serotonin induced hypothermia and diarrhea].[Article in Japanese] by Huang Q1, Matsuda H, Sakai K, Yamahara J, Tamai Y. (PubMed)