Saturday, 13 July 2019

Bromelain Improves the Neurological Status in Post Acute Infarction

By Kyle J. Norton

Acute brain infarction is the medical condition characterized by the obstruction of the blood supply to the brain, causing local death of the brain tissue.

The occurrence and extent of brain infarction are asscoaited with three basic factors, including the site of arterial occlusion,  the rapidity of arterial occlusion, and the presence or absence of collateral circulation.

In other words, brain infarction can be classified into myocardial infarction due to plaque rupture and myocardial oxygen supply-demand imbalance secondary to other acute illnesses.

Most common symptoms of acute brain infarction are trouble with speaking and understanding,  confusion, sudden numbness, weakness or paralysis in your face, arm or leg, headache and the trouble with walking.

Depending on the severity of the acute infarction, in serious cases, patients may also experience symptoms, paralysis of the face, arm or leg, trouble with seeing in one or both eyes.

Acute brain infarction is a medical emergency, Prompt treatment can minimize brain damage and potential complications.

There are many factors associated with the risk of acute infarction. However, aging may have a strong and negative implication on acute infarction.

Dr. Mehta RH, the lead scientist wrote, "Older age was associated with a greater proportion of patients with functional limitations, heart failure, prior coronary disease, and renal insufficiency and a lower proportion of male and diabetic patients".

And, "...age-associated differences in clinical characteristics in elderly patients with acute myocardial infarction (AMI), which account for some of the age-associated differences in mortality".

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

On finding a potential compound for the treatment of complications after acute brain infarction, researchers examined the effect of Flogensim on the neurological status on 1st and 7 days after developing the disease.109 patients.

Where Flogenzim consists of highly active proteolytic enzymes containing bromelain, trypsin and of Rutinum.

According to the tested analysis, on day 7, Flogenzim treatment group showed a decrease in the concentration of I1-6, compared to control.

Where high levels of interleukin-6 (I1-6) is associated with postischemic inflammation in patients with acute brain infarction.

Furthermore, on day 21 among patients pertaining to a different group, the considerable difference in consequences were better increases in the treatment group.

More profoundly, the number of patients of Flogenzim group showed no dynamic or even worsening in neurological status decreases, compared to control.

Taken altogether, bromelain used alone or combined with other remedies may be considered a remedy for the improvement of neurological status, pending to the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [Effect of flogensim in the treatment of postischemic inflammation (according to results of using interleukin-6 in patients with acute brain infarction)].[Article in Ukrainian] by Vinychuk SM, Cheren'ko TM. (PubMed)
(2) Acute myocardial infarction in the elderly: differences by age by Mehta RH1, Rathore SS, Radford MJ, Wang Y, Wang Y, Krumholz HM. (PubMed)

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