Eggplant is a species of S. melongena with deeply purple color, belongings to the family Solanaceae and native to India, cultivated in southern and eastern Asia since prehistory.
Lung cancer is medical condition characterized by irregular cell growth in the issues of lung At the later stage, the cancerous cell may invade other healthy tissues and organs a distance away from the original site.
According to statistic, approximately 28,600 Canadians will be diagnosed with lung cancer represented 14% of all new cancer cases in 2017.
Additionally, injection of solasodine promoted cancer cells death was also associated to the over expression of tissue inhibitor of metalloproteinase-1 (TIMP-1), a glycoprotein found in several tissues of organisms with function in involved in degradation of the extracellular matrix as mention above and TIMP-2, a member of the TIMP gene family with function as a metastasis suppressor.
Finally, solasodine decreased expression of microRNA-21 which has been found to be higher in more advanced malignancies, in initiated early entry phase of cancer developing by stimulated production of RECK in accelerated cancer cell proliferation, thus decreasing risk of cell invasion.
After taking into account of all con founders, Dr. Shen KH, the lead author said, "the findings demonstrate an attractive therapeutic potential for solasodine in lung cancer anti-metastatic therapy".
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Impact In Rice, Pasta, And Potatoes In Half
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Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Solasodine inhibits invasion of human lung cancer cell through downregulation of miR-21 and MMPs expression by Shen KH1, Hung JH2, Chang CW2, Weng YT2, Wu MJ2, Chen PS3.(PubMed)
(2) Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes by Friedman M1.(PubMed)