Friday, 26 January 2018

Alternative Therapy: Yoga in Modulation of Immune Response

Kyle J. Norton 

Yoga may be considered as a home base exercise in improved immune response against foreign substances invasion according to online public medical studies.

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the study by Dr. Arora S and colleagues, yoga practice regularly may reduce risk of stress influenced in immune expression through deactivation of many connected mechanisms, including  reduced alterations in the number of immune cells and cytokine dysregulation.

Yoga therapy has been found to reduce the psychological and physiological effects of stress in cancers and HIV infection.

In deed, yoga intervention improved the immune lymphocytes (T cells) in cell-cell interaction and the release of mediators such as antibodies (in the case of B cells), cytotoxic granules (cytotoxic T cells) or by signaling to other cells of the immune system in inhibited antigen. 

Immune dysfunction caused by long term stress has been found to have strong implications in reduced immune response to foreign substances invasion, including vaccines, delayed wound healing and improper reaction to infectious diseases.

In further demonstration of yoga effect in increased immune response, the Lady Hardinge Medical College carried out a study included sixty first-year MBBS students randomly assigned to yoga group and control group (30 each), with yoga group underwent integrated yoga practices for 35 minutes daily in the presence of trained yoga teacher for 12 weeks and control group did not undergo any kind of yoga practice or stress management, after taking into account of other co founder, demonstrated that
* There was no significant difference observed in physiological parameters during the examination stress, in compared to a significantly increased stress in control
* Indicator of expressed assay also found higher stress in the control than those in yoga group
* Hormone status also showed the increased serum cortical and decreased serum IFN-Ī³ in yoga group was less significant (P<0.01) than in the control group.
* Yoga displayed a lesser inflammatory status in compared to control

Dr. Gopal A, the led author said, "Yoga resists the autonomic changes and impairment of cellular immunity seen in examination stress".

Truly, Yoga participation in exertion of ameliorated stress on immune system was found to be mediated by a complex network of signallings involving various aspects including nervous, endocrine, and immune systems through expression and interaction of neurotransmitters, neuropeptides, hormones, and cytokines, according to Dr. Sarika Arora and Jayashree Bhattacharjee.

The endocrine-immune system network including adrenal and pituitary glands secreted hormone binding to receptors of white blood cell in response to expression of the release of cytokines in the acute phase and chronic inflammation and these hormones and cytokine concentration are alternated in patients with prolonged stress.

These results according to some yoga instructors were attributed to the effect of yoga relaxation and meditation in stimulated production of a steroid hormone called glucocorticoids (GCs) which has been found to enhance the immune systems and prevented immune abnormal activity.

Some researchers suggested that such change(hormones and cytokine concentration are alternated in patients with prolonged stress.) subsequently induced immune dysfunction, leading to abnormal sleep pattern and  behavioral changes such as a reduction in activity, social interaction, sexual activity and psychological expression of increased responsiveness to pain, anorexia, and depressed mood.

Further to support the effects of yoga intervention in improved immune response, researchers at the joint study led by the Healthcare Global, conducted a study of 91 patients with metastatic breast cancer satisfied selection criteria, randomly assigned to receive "integrated yoga based stress reduction program" (n = 45) or standard "education and supportive therapy sessions" (n = 46) over a 3 month period, showed that
* Participants expressed a strong improvement of symptom distress, sleep parameters and quality of sleep and insomnia .
* Yoga lesson also decreased in morning waking cortisol in compared to standard group
* Yoga group displayed a significant improvement in NK cell percent

Taking altogether, the finding evidences suggested that yoga intervention may have a positive and profound effect in improved immune response when come under attacks by foreign substances invasion, including virus and bacteria.

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Author Biography
Kyle J. Norton (Scholar, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

(1) Modulation of immune responses in stress by Yoga by Arora S, Bhattacharjee J.(PubMed)
(2) Effect of integrated yoga practices on immune responses in examination stress - A preliminary study by Gopal A1, Mondal S, Gandhi A, Arora S, Bhattacharjee J.(PubMed)
(3) Effect of Yoga on Sleep Quality and Neuroendocrine Immune Response in Metastatic Breast Cancer Patients by Rao RM1, Vadiraja HS2, Nagaratna R2, Gopinath KS3, Patil S4, Diwakar RB4, Shahsidhara HP4, Ajaikumar BS5, Nagendra HR6.(PubMed)
(4) Modulation of immune responses in stress by Yoga by Sarika Arora and Jayashree Bhattacharjee(PMC)

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