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Monday, 12 May 2014

Herbal Butcher's broom

Butcher's broom is a low evergreen shrub, a species of Ruscus aculeatus, belonging to the family Asparagaceae, native to Eurasia.It has been used in herbal medicine to treat reduce inflammation, Peripheral vascular disease, Hemorrhoids Bronchial asthma, Varicose veins, Hypotension, Jaundice, functional disorders of the heart, kidney disorder, venotonic and anti-oedematous properties, etc..

The Ingredients
It contains rutin, sitosterol, sparteine, spirostanol saponins, steroidal sapogenins, sterols, stigmasterol, sulfated steroidal saponins, sweet broom, tetracosanoic acid, triterpenes, triterpines, tyramine, etc.

1. Butcher's broom and Orthostatic hypotension (OH)
Orthostatic hypotension (OH), also known as postural hypotension of which happens when a person stands up from sitting or lying down or in sudden adjustment of body position, the blood pressure falls, and a person may experience lightheaded or even pass out.

The benefits 
 In most cases, Orthostatic hypotension (OH) affects affects large groups of the population with autonomic insufficiency--the elderly; patients with diabetes, Parkinson's disease, and chronic fatigue syndrome; and anyone on drugs that affect the autonomic nervous system. In conventional medicine, most cases of Orthostatic hypotension (OH)are treated with fludrocortisone and midodrine. In the study by the American University, to evaluate the properties of Ruscus aculeatus, its mechanism of action, and its suitability as a therapeutic agent for treatment of OH, showed that with proven phlebotherapeutic properties, including vasoconstrictive action and venotonic properties, Ruscus aculeatus shows great promise for ameliorating the symptoms of OH and improving the quality of life for large groups in the population without increasing supine blood pressure.

Reference
1. Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report. by Redman DA.(PubMed).

2. Herbal Butcher's broom and Chronic venous insufficiency
Chronic venous insufficiency is defined as a condition of veins do not return enough oxygen-poor blood back to the heart.

The benefits
Extracts from Butcher's broom rhizome (Ruscus aculeatus) is found to be efficacy in treating patients  with chronic venous insufficiency, as the change of leg volume after 8 and 12 weeks of treatment (-16.5 ml and -20.5 ml), for changes in ankle and leg circumferences after 8 and 12 weeks of treatment, and for the changes in subjective symptoms, heavy tired legs and sensation of tension (week 12) and the reduction of symptoms heavy lower legs, sensation of tension, and tingling sensation a significant positive correlation with the changes in leg volume. Other in the study of the effects of Ruscus aculeatus, hesperidin methyl-chalcone and ascorbic acid (HMC-AA), in chronic venous disorders (CVD, a 12-week treatment with Ruscus aculeatus HMC-AA improve quality of life by significantly decrease in the clinical symptoms and a significant improvement in the QoL of patients with CVD.

References
(1) Efficacy and safety of a Butcher's broom preparation (Ruscus aculeatus L. extract) compared to placebo in patients suffering from chronic venous insufficiency BY Vanscheidt W, Jost V, Wolna P, Lücker PW, Müller A, Theurer C, Patz B, Grützner KI.(PubMed)
(2) Assessment of quality of life in Mexican patients suffering from chronic venous disorder - impact of oral Ruscus aculeatus-hesperidin-methyl-chalcone-ascorbic acid treatment - 'QUALITY Study by Guex JJ, Enriquez Vega DM, Avril L, Boussetta S, Taïeb C.(PubMed)
(3)  Chronic venous insufficiency http://www.vascularweb.org/vascularhealth/Pages/chronic-venous-insufficiency.aspx

3. Herbal Butcher's broom and Inflammatory effects
Inflammation is a condition of Immune system self-protection to remove harmful stimuli, including damaged cells, irritants, pathogens... from our body.

The benefits
Ruscogenin (RUS), isolated from Ruscus aculeatus, has been found to exert significant anti-inflammatory and anti-thrombotic activities by inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. Other study also showed ruscogenin resulted in markedly reduced expression of inflammatory cytokine and leukocyte infiltration via the inhibition of nuclear factor (NF)-κB activity in rat lungs.
 
References
(1) Possible mechanism of the anti-inflammatory activity of ruscogenin: role of intercellular adhesion molecule-1 and nuclear factor-kappaB by Huang YL, Kou JP, Ma L, Song JX, Yu BY.(PubMed)
(2) Ruscogenin attenuates monocrotaline-induced pulmonary hypertension in rats  by Bi LQ, Zhu R, Kong H, Wu SL, Li N, Zuo XR, Zhou SM, Kou JP, Yu BY, Wang H, Xie WP.(PubMed)

4. Herbal Butcher's broom and varicose veins

Varicose veins is a condition of which the veins have become enlarged and twisted


The benefits
Surgery, includes injection/compression sclerotherapy and surgical stripping or ligation or both always is the first recommendation for patients with varicose disease. Ruscus aculeatus has been found to relieve the symptoms of  pain, and expensive complications of varicose veins by improving microcirculation, capillary flow, and vascular tone, and to strengthen the connective tissue. Other study suggested that venotropic agents from plant extract probably exert effects by way of multiple receptor and non-receptor mediated events as  the differential distribution of alpha adrenergic receptors on greater saphenous veins from non-varicose patients compared to those with primary varicose disease.

References
(1) Hemorrhoids and varicose veins: a review of treatment options by MacKay D.(PubMed)
(2) Selecting a treatment for primary varicose veins by Tremblay J, Lewis EW, Allen PT.(PubMed)
(3) Pharmacological assessment of adrenergic receptors in human varicose veins by Miller VM, Rud KS, Gloviczki P.(PubMed)

5. Herbal Butcher's broom and hemorrhoids
Hemorrhoids are sw
ollen veins in the anal canal of which cause cause pain and in some cases, life threatening if patients loss a large volume of blood. Approximately, 75% of all Americans will develop hemorrhoids at some points in their lives.


The benefits
Oral supplementation of Ruscus aculeatus is found to be effective in preventing time-consuming, painful, and expensive complications of  hemorrhoids, such as anal discomfort, soiling and bleeding pre- sent in acute phase. Other hemorrhoids an open trial, also found the positive effect of Butcher’s broom, with 75 percent of participating physicians rating butcher’s broom’s efficacy as good or excellent


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References
(1) Hemorrhoids and varicose veins: a review of treatment options by MacKay D.(PubMed)
(2) ANTIOXIDANT HERBAL SUPPLEMENTS FOR HEMORRHOIDS Developing a new formula, by Silvia Vertuani, Elena Bosco, Micaela Testoni, Simona Ascanelli, Gianfranco Azzena, Stefano Manfredini(2004, 3(3) 19-26)
(3) Page 608 Alternative Medicine Review Volume 6, Number 6 2001 Copyright©2001 Thorne Research, Inc. All Rights Reserved. No Reprint Without Written Permission Ruscus aculeatus (Butcher’s Broom)

Side effects
1. Do not use if you are pregnant with out permission of related field specialist, as Sparteine may increase uterine contraction
2. Do not use Butcher's broom if you are taking any form of monoamine oxidaseinhibitor
3. Use as direction and do not overdose
4. Etc.