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Friday, 23 May 2014

Avocado and Cardiovascular disease

Avocado is commercially valuable fruit cultivated in tropical climates throughout the world, it is a green-skinned, pear-shaped fruit that ripens after harvesting and native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae.
Nutrients
1. Vitamin K
2. Dietary fiber
3. Vitamin B6
4. Vitamin C
5. Folate
6. Copper
7. Potassium
8. Amino acid
9. Others
a) Vitamin A
b) Vitamin B1, B2, B3, B12
c) Vitamin D
d) Vitamin E
e) Carotenoid
f) Pantothenic acid
g) Calcium
h) Chromium
Chemical constituents
The fruit contains campesterol, high amounts of β-sitosterol (average 76.4 mg/100 g); fatty acids (approximately 60% monounsaturated, 20% saturated, and 20% unsaturated); high amounts of glutathione (27.7 mg/100 g); approximately 2% protein; 6–9% carbohydrates and sugars (glucose, fructose, d-mannoheptulose, a taloheptulose, and an alloheptulose); two bitter substances (1-acetoxy-2,4-dihydroxyheptadeca-16-ene and 1,2,4-trihydroxyheptadeca-16-ene); carnitine; proanthocyanidins; persenones A and B(a).


Heart diseases are caused by high blood pressure that contributes to hardening of the arteries. High levels of bad cholesterol (LDL) building up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat.
In animal study,  Persea americana Mill (Lauraceae) aqueous leaf extract (PAE) showed an significant effect in reduced risk and treatment of heart diseases, through its hypotensive (antihypertensive) effects(1). According to Nutrition Science Solutions LLC, consumption of one-half an avocado (68 g), not only provided many nutrients which are necessary for body needed, but also supported cardiovascular health(2).
The National Health and Nutrition Examination Survey (NHANES) 2001-2008, suggested that avocado consumption is associated with improved overall diet quality, nutrient intake, and reduced risk of metabolic syndrome(3), including cardiovascular disease.


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References
(a) Leung's Encyclopedia of Natural Ingredients:Chemical Composition of Avocado
(1) Cardiovascular effects of Persea americana Mill (Lauraceae) (avocado) aqueous leaf extract in experimental animals by Ojewole JA1, Kamadyaapa DR, Gondwe MM, Moodley K, Musabayane CT.(PubMed)
(2) Hass avocado composition and potential health effects by Dreher ML1, Davenport AJ.(PubMed)
(3) Avocado consumption is associated with better diet quality and nutrient intake, and lower metabolic syndrome risk in US adults: results from the National Health and Nutrition Examination Survey (NHANES) 2001-2008 by Fulgoni VL 3rd1, Dreher M, Davenport AJ.(PubMed)