Wednesday 30 October 2013

Chinese Herbs – Zhe Bei Mu (Bulbus Fritillariae Thunbergii)

Zhe Bei Mu is also known as Thunberg Fritillary Bulb. The bitter and cold herb has been used in TCM to suppress cough, expels phlegm, Small amount of the saponin can raise blood pressure, while large amount can lower it, etc., as it transforms Phlegm, calms cough, clears Heat, dissolves nodules, etc., by enhancing the functions of heart and lung channels.

Ingredients
1. Peimine
2. Peiminine
3. Propeimine
4. Peimidine
5. Peimiphine
6. Peimisine
7. Peimitidinek
8. Isoverticine
9. Peimisnoside
10. Etc.

Health Benefits
1. Anti-allergy effect
In the study to investigate the mechanism of the anti-allergy effect of FU. FU extract (80 mg/kg), orally administered to Sprague-Dawley (SD) rats, showed that treatment with FU attenuated PMA plus A23187-induced phosphorylation of all three MAPKs, especially at concentrations of 10 and 100 µg/mL. Further, it (80 mg/kg) led to significant inhibition of mast-cell accumulation in ear tissue at the chronic phase. These results indicate that it inhibits allergic reactions(1).
2. Cancerous Cell apoptosis
In the study to investigate the effects of the Compound Fritillaria thunbergii Miq Particles (CFMP) to the sub-cellular accumulation ability and inducing the apoptosis of K562/A02 cells and explore the mechanism of the CFMP reserve the multi-drug resistance of K562/A02 cells, showed that CFMP can inhibit the descend trend of the ADR and Rh123 fluorescence accumulation curve of K562/A02 cells, induce the apoptosis of K562/A02 cells to achieve the reverse intention of multi-drug resistance(2).
3. Etc.

Side Effects
1. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
2. Do not use the herb in case of spleen deficiency with damp phlegm or cold cough
3. Etc.


Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21821956
(2 http://www.ncbi.nlm.nih.gov/pubmed/20462045

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