1. Antioxidant effects
In the study to document the antioxidant potential of ethanolic extract of Rumex patientia L. (Polygonaceae) roots and its chemopreventive effects against Fe-NTA mediated hepatic oxidative stress, hepatotoxicity and tumor promotion response, showed that the efficacy of extract was also evaluated in vivo and it was found to exert a potent protective affect in acute oxidative tissue injury animal model: ferric nitrilotriacetate (Fe-NTA) induced hepatotoxicity in mice. Administration of Fe-NTA (9 mg/kg body weight, i.p.) to mice led to a significant oxidative stress and allied damage in liver tissues and induced hyperproliferation. A significant depletion was observed in GSH content and enzymes implicated in its metabolism. Attenuation also occurred in activities of other hepatic antioxidant enzymes including SOD, CAT, and GPX. Fe-NTA also incited hyperproliferation response elevating ornithine decarboxylase activity and [(3)H]-thymidine incorporation into DNA(1).
2. Anti-ulcerogenic activity
In the evaluation of their anti-ulcerogenic potential of decoctions prepared from aerial parts of Malva neglecta Wallr. (Malvaceae), leaves of Potentilla reptans L. (Rosaceae), fruits of Rumex patientia L. (Polygonaceae), aerial parts of Sanguisorba minor Scop. ssp. muricata (Spach) Briq. (Rosaceae), aerial parts of Sideritis caesarea Duman, Aytac&Baser (Lamiaceae), and flowers of Verbascum cheiranthifolium Boiss var. cheiranthifolium (Scrophulariaceae) according to their described folkloric applications, indicated that the extracts of all plants given orally showed significant gastric protection against the ethanol-induced gastric ulcer model in rats. Furthermore, healing effects were also confirmed through histopathological examination(2).
3. Anti inflammatory effect
In the study to evaluate the aqueous extract of roots of Rumex patientia L. (Polygonaceae) on experimental animals for its the antiinflammatory activity, found that it possess antiinflammatory activity. Acute toxicity studies revealed that the extract up to a dose of 3 mg/kg orally was nontoxic(3).
4. Analgesic and antipyretic activities
The aqueous extract from the roots of Rumex patientia L. (Polygonaceae) possess significant analgesic and antipyretic activities in the study on mice and rabbits(4).
5. Gastroprotective and antiulcerogenic effects
In the comparison of the Gastroprotective and antiulcerogenic effects of the aqueous extract of Rumex patientia L. roots (D-1) with non-steroidal antiinflammatory drugs (NSAIDs), found that In rats, the number of stress ulcers induced by the administration of 150 mg/kg of D-1 were identical to that of the control group. However, compared to the control group, the number of stress ulcers decreased 1.9 times and the size of ulceration areas decreased 1.1 times in the group treated with 500 mg/kg of D-1(5).
1. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
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