Ye Ju Hua is also known as Wild Chrysanthemum.
The acrid, bitter and slightly cold has been used in TCM to treat sore
swollen throats, boils, carbuncles and sores, etc., as it clears Heat,
expels toxins, etc, by enhancing the functions of lung and liver
channels.
Ingredients
1. Acacetin-7-rhamnosidoglucoside
2. Yejuhua lactone
3. Chrysanthemin
4. Physalin
5. α-thuJone
6. Artoglasin-A
7. Acaciin
8. Etc.
Health Benefits
1. Multidrug resistance in cancer cells
In the study the fractions from 17 clinically used antitumour traditional Chinese medicinal herbs were tested for their potential to restore the sensitivity of MCF-7/ADR and A549/Taxol cells to a known antineoplastic agent, showed that five herbs (Curcuma wenyujin, Chrysanthemum indicum, Salvia chinensis, Ligusticum chuanxiong Hort. and Cassia tora L.) could sensitise these resistant cancer cells at a non-toxic concentration (10 µg mL⁻¹), and markedly increased doxorubicin accumulation in MCF-7/ADR cells(1).
2. Prostate cancer
In the study to evaluate the potential effects of C. indicum on signal transducer and activator of transcription 3 (STAT3) signaling pathway in different tumor cells, showed that the methylene chloride fraction of C. indicum (MCI) exhibited strong cytotoxic activity as compared with the other fractions and clearly suppressed constitutive STAT3 activation against both DU145 and U266 cells, but not MDA-MB-231 cells. The suppression of constitutive STAT3 activation by MCI is associated with blocking upstream JAK1 and JAK2, but not Src. MCI downregulated the expression of STAT3-regulated gene products; this is correlated with the accumulation of the cell cycle at sub-G1 phase, the induction of caspase-3 activation, and apoptosis(2).
3. Atopic dermatitis (AD)
In the study to investigate the atopic dermatitis (AD) effect of topically applied CIL in mice with AD-like symptoms. After topical application of 1,3-butylen glycol (control), CIL-Low (5%), CIL-High (30%), or 0.1% hydrocortisone (HC) on the AD-like skin lesions in DNCB-treated NC/Nga mice for 5 weeks, the ear thickness, mast cell infiltration, and serum immunoglobulin E (IgE), IgG1, IL-4 and interferon (IFN)-γ were measured(3).
4. Ventricular system
In the study to explore the effects and mechanism of Chrysanthemum indicum on experimental ventricular remodeling induced by isoprenaline (ISO) and L-thyroxine (L-Thy), found that chrysanthemum indicum can significantly attenuate the experimental ventricular remodeling; the mechanism may be related with restricting the activity of the sympathetic nervous system and decreasing the levels of Ang II, ALD and TNF-alpha(4).
5. Etc.
Side Effects
1. Overdose may cause nausea, vomiting, lack of appetite, flatulence, etc.
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21848372
(2) http://www.ncbi.nlm.nih.gov/pubmed/22438130
(3) http://www.ncbi.nlm.nih.gov/pubmed/22454686
(4) http://www.ncbi.nlm.nih.gov/pubmed/21137368
Ingredients
1. Acacetin-7-rhamnosidoglucoside
2. Yejuhua lactone
3. Chrysanthemin
4. Physalin
5. α-thuJone
6. Artoglasin-A
7. Acaciin
8. Etc.
Health Benefits
1. Multidrug resistance in cancer cells
In the study the fractions from 17 clinically used antitumour traditional Chinese medicinal herbs were tested for their potential to restore the sensitivity of MCF-7/ADR and A549/Taxol cells to a known antineoplastic agent, showed that five herbs (Curcuma wenyujin, Chrysanthemum indicum, Salvia chinensis, Ligusticum chuanxiong Hort. and Cassia tora L.) could sensitise these resistant cancer cells at a non-toxic concentration (10 µg mL⁻¹), and markedly increased doxorubicin accumulation in MCF-7/ADR cells(1).
2. Prostate cancer
In the study to evaluate the potential effects of C. indicum on signal transducer and activator of transcription 3 (STAT3) signaling pathway in different tumor cells, showed that the methylene chloride fraction of C. indicum (MCI) exhibited strong cytotoxic activity as compared with the other fractions and clearly suppressed constitutive STAT3 activation against both DU145 and U266 cells, but not MDA-MB-231 cells. The suppression of constitutive STAT3 activation by MCI is associated with blocking upstream JAK1 and JAK2, but not Src. MCI downregulated the expression of STAT3-regulated gene products; this is correlated with the accumulation of the cell cycle at sub-G1 phase, the induction of caspase-3 activation, and apoptosis(2).
3. Atopic dermatitis (AD)
In the study to investigate the atopic dermatitis (AD) effect of topically applied CIL in mice with AD-like symptoms. After topical application of 1,3-butylen glycol (control), CIL-Low (5%), CIL-High (30%), or 0.1% hydrocortisone (HC) on the AD-like skin lesions in DNCB-treated NC/Nga mice for 5 weeks, the ear thickness, mast cell infiltration, and serum immunoglobulin E (IgE), IgG1, IL-4 and interferon (IFN)-γ were measured(3).
4. Ventricular system
In the study to explore the effects and mechanism of Chrysanthemum indicum on experimental ventricular remodeling induced by isoprenaline (ISO) and L-thyroxine (L-Thy), found that chrysanthemum indicum can significantly attenuate the experimental ventricular remodeling; the mechanism may be related with restricting the activity of the sympathetic nervous system and decreasing the levels of Ang II, ALD and TNF-alpha(4).
5. Etc.
Side Effects
1. Overdose may cause nausea, vomiting, lack of appetite, flatulence, etc.
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21848372
(2) http://www.ncbi.nlm.nih.gov/pubmed/22438130
(3) http://www.ncbi.nlm.nih.gov/pubmed/22454686
(4) http://www.ncbi.nlm.nih.gov/pubmed/21137368
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