Monday 16 December 2019

Turmeric Postpones the Onset of Age-Related Disease

By Kyle J. Norton

Age-related diseases are medical conditions associated with the increase of age.

Most recently age-related diseases in the elderly are cardiovascular diseases.

Cardiovascular diseases are a group of conditions triggered by the abnormal function of the heart and blood vessels abnormality.

The 3 most common forms of cardiovascular disease in North America are coronary artery disease, peripheral artery disease, and carotid artery disease caused by plaques build-up of plaque in the arteries that supply blood to the heart, the arms and legs, and the brain, respectively.

*Cancer
Cancer is a group of medical and chronic diseases characterized by cell growth disorderly and uncontrollably in the tissue of specific organs in the body.

Over time, the alternative cells induced tumor may become progressively worse and damage other healthy tissues, depending on the grade of the tumor.

*Rheumatoid Arthritis is a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing the diminished quality of life of many elders(1).

* Cataracts
A cataract is a condition of clouding, developed in the crystalline lens of the eye. The condition mostly happens to the elder and in case of severity, it can be complete opacity and obstructing the passage of light.

* Osteoporosis
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence invertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries.

*Type 2 diabetes
Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate glucose due to either cell in the pancreas dying off or receptor sites clogged up by fat and cholesterol.

*Hypertension 
Hypertension is a condition characterized by persistently high blood pressure.

* Alzheimer's disease.
Age-related neurological disorders or neurodegenerative diseases are the conditions of the progressive death of neurons due to aging, leading to the problems with movement (called ataxias), or mental functioning including Alzheimer's disease (AD) and dementia.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

In the urgency to discover a natural ingredient for the prevention of chronic inflammatory diseases, researchers examined the effects of curcumin on aging and age-related diseases.

According to the tested analysis, injection of curcumin showed a strong activity against low-grade inflammation driven by oxygen stress in the induction of the increased level of pro-inflammatory cytokines such as IL-1, IL-6, and TNF-α.

Furthermore, the anti-aging-related diseases involved in low-grade inflammation of curcumin were attributed to the inhibiting genes activated by the transcription factor NF-κB. 

In other words, curcumin slowed down the aging process and postponed the onset of age-related diseases by blocking the NF-κB-dependent inflammation

Based on the findings, researchers said, " We consider the possibility of the spice curcumin, a powerful antioxidant and anti-inflammatory agent possibly capable of improving the health status of the elderly".

Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the prevention of aging related-diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin, inflammation, ageing and age-related diseases by E Sikora,1 Giovanni Scapagnini,2 and Mario Barbagallo. (PubMed)

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