Friday 13 December 2019

Daily Non-Soy Legume Intake Reverses the Parameters Associated with Peripheral Artery Disease.

By Kyle J. Norton

Peripheral artery disease is a common circulatory condition caused by narrowed arteries that reduce blood flow to your limbs.

Most cases of peripheral artery disease have been associated with the accumulation of plaque in thicking and hardening the arteries, a leading cause of atherosclerosis.

The most common prevalent factors associated with peripheral artery disease are tobacco, physical inactivity, and an unhealthy diet with high in fat, processed food, and red meat and low in fruits and vegetables.

Most patients with peripheral arterial disease are asymptomatic or experience a mild case of pain in the leg while walking. However, as the disease progression, some patients may also experience symptoms of leg numbness or weakness, coldness in your lower leg or foot, sores on your toes, feet or legs that won't heal, a change in the color of your legs, slower growth of your toenails and shiny skin on your legs.

Some men also experience the syndrome of erectile dysfunction in severe cases.

Conventionally, the treatment of peripheral arterial disease is focusing to improve symptoms, such as leg pain, and quality of life and stopping the progression of atherosclerosis associated with the risk of heart attack and stroke, including medication to lower cholesterol, blood pressure and blood sugar.

In some cases, surgery may be necessary to treat peripheral artery disease if patients experience claudication that does not respond to medicine.

A legume is a plant in the family Fabaceae that fruit or seed of a plant.

On finding a potent ingredient for the treatment of associated with atherosclerotic plaque, researchers investigated the effect of consuming whole legumes (non-soy) on arterial function in humans with peripheral artery disease (PAD).

The study included a total of 26 individuals with PAD consumed ½ cup/day cooked legumes (beans, peas, lentils, chickpeas) daily for 8 weeks.

Compared to the baseline, consumed ½ cup/day cooked legumes showed a reduced total and LDL-cholesterol to 5.0% from 8.7%, short-chain acylcarnitine concentrations and increased ankle-brachial index (ABI) by 5.5%, without affecting other parameters.

In other words, legume-rich diet improved in arterial function and serum cholesterol with no effects on body mass or blood pressure.

However, due to the limitation of the study, researchers said, "Although the positive results obtained with this dietary intervention were not explained by biomarkers of endothelial function and inflammation, altered acylcarnitine levels indicate an improvement in skeletal muscle metabolism due to enhanced tissue perfusion".

Taken altogether, daily non-soy legume consumption may be considered functional foods for the prevention and treatment of peripheral artery disease,  pending to the confirmation of the larger sample size and multicenter human study.



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease by Zahradka P1, Wright B, Weighell W, Blewett H, Baldwin A, O K, Guzman RP, Taylor CG. (PubMed)

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