Dementia is a medical and neurodegenerative disease characterized by the loss of mental ability, that is severe enough to interfere with people's every life.
Alzheimer's disease and Parkinson's disease (PD) are the most common types of dementia in aging people.
Parkinson's disease (PD) is a type of dementia that affects the nerve cells associated with the production of dopamine in the brain, leading to muscle rigidity, tremors, and changes in speech and gait.
In other words, Parkinson's disease is a progressive neurological disorder that affects neurons in transmitting messages in controlling the movement.
In the very early stage of PD, patients may not experience any symptoms. However, Parkinson's disease symptoms gradually worsen as the condition progresses.
As of today, researchers do not know why the neurons in the brain in some people are susceptible to gradually break down or die while others do not even they have similar health conditions and from the same family.
Epidemiologically aging, gender, long-term exposure to certain toxic chemicals and genetic deposition are some of the prevalent factors involved in the increased risk of the disease.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the prevention and treatment of neurological disorders, researchers examined the effects of Centella asiatica and Withania somnifera root extract consumption on Parkinson's disease in an animal model.
On 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced Parkinson-like symptoms Balb/c mice, both ethanol extracts significant reduced the tested mice oxidative stress profile.
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and treatment of Parkinson's disease symptoms, pending to the result of larger sample size and multicenter study
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Complete Comparison Display (CCD) evaluation of ethanol extracts of Centella asiatica and Withania somnifera shows that they can non-synergistically ameliorate biochemical and behavioural damages in MPTP induced Parkinson'smodel of mice by Bhatnagar M1, Goel I2, Roy T3, Shukla SD1,4, Khurana S. (PubMed)