Thursday, 26 December 2019

Dandelion (Taraxacum officinale) Processes a Strong Antifungal Activity

By Kyle J. Norton

Fungal infection is a common disease caused by the overgrowth of fungus.

In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.

Yeasts, molds, and mushrooms are types of fungi. The tiny microorganisms have cells with nuclear.

Most common fungal infections start from the lungs or the skin. Long-term use of antibiotics and people with the weakened immune system are susceptible to fungal infection, epidemiologically.

However, some researchers suggested that common risk factors for fungal infection also include pregnancy, diabetes mellitus, oral contraceptives, and inadequate therapy.
People with weakened immune systems such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.

Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes includes jock itch, athlete's foot,..... and ringworm.

Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,...... and burning sensation.

In women, signs of a yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........ and unusual vaginal discharge.

In men, signs of a yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of fungal infectious diseases,
scientists examined the antifungal effects of novel peptide named ToAMP4 isolated from Taraxacum officinale Wigg. flowers by a combination of acetic acid extraction and different types of chromatography.

According to the tested differentiation of the biological activity of ToAMP4 produced in a prokaryotic expression system as a fusion protein with thioredoxin, the peptide  ToAMP4 displayed broad-spectrum antifungal activity against phytopathogens.

Moreover, the two ToAMP4 also exerted significantly mediated inhibition properties, on the tested fungus

In other words, ToAMP4 processed anti-fungal infection depending on the types of fungus.

Taken altogether, dandelion may be considered a remedy for the prevention and treatment of fungal infection, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A novel cysteine-rich antifungal peptide ToAMP4 from Taraxacum officinale Wigg. flowers by Astafieva AA1, Rogozhin EA, Andreev YA, Odintsova TI, Kozlov SA, Grishin EV, Egorov TA. (PubMed)

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