A neuron is a nerve cell that forms a building block of the nervous system.
Neuroblastoma is cancer developed by the immature nerve cells found in several areas of the body, mostly in and around the adrenal glands.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the protection of neurons, researchers examined the effects of ashwagandha root extract consumption on human neuroblastoma (IMR32).
Human neuroblastoma (IMR32) cells, pretreated with Ashwagandha-reagents for 24 h, were exposed to H2O2 (300 μM) for 2 h, before incubating in control or test medium supplemented with either the alcoholic (i-Extract) or water (WEX) extracts or their active components (withanone or withaferin A), showed a significant effect on H2O2 by 40%.
Taken altogether, Ashwagandha may be considered a functional herb that protects the neurons against the onset of neuroblastoma, pending to the result of larger sample size and multicenter study
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Combinations of Ashwagandha Leaf Extracts Protect Brain-Derived Cells against Oxidative Stress and Induce Differentiation by Navjot Shah, 1 Rumani Singh, 1 Upasana Sarangi, 1 Nishant Saxena, 1 Anupama Chaudhary, 1Gurcharan Kaur, 2 Sunil C. Kaul, 1,* and Renu Wadhwa. (PMC)