Thursday 26 December 2019

Legume Protects the Liver Cells Against the Rick of Nonalcoholic Fatty Liver Disease

By Kyle J. Norton

The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm and above your stomach.

The liver not only plays a critical role to filter the blood coming from the intestine before passing them to other parts of the body but also protects our body against toxin by detoxifying chemicals and metabolizes drugs.

Furthermore, the liver produces bile that not only aids the digestive function in food absorption but also builds strong cell membranes, produces vitamin D and steroid hormone.

Liver disease in most cases is linked to alcohol or drugs. In fact, it can be caused by a variety of factors and affecting everyone from infants to older adults, including infected viri such as hepatitis A, B, C, and medication overloaded.

Nonalcoholic fatty liver disease (NAFLD) is one of the major causes of cirrhosis and liver cancer.

Nonalcoholic liver disease is a chronic condition caused by fat accumulated over time in the liver, affecting people who drink little to no alcohol.

In other words, if you have fat that makes up over 5% of the liver, you are considered to have fatty liver disease.

Nonalcoholic liver disease can be classified into the noninflammatory fatty liver and inflammatory liver steatohepatitis.

According to world statistics, nonalcoholic fatty liver disease (NAFLD) is normally known as a disease of the Western world(2). However, due to the economic prosperity of Southeast Asian(3), the disease also was found in a large population in the cities, causing concerns of many scientists in the region(4)(6).

According to the joint assessment of the prevalence of non-alcoholic fatty liver disease and risk factors for advanced fibrosis and mortality in the US, led by the Stanford University School of Medicine, "The prevalence of NAFLD in the United States (U.S.) has risen from 18% in 1988–1991 to 31% in 2011–2012. Estimates of NAFLD prevalence for adults in Western countries are 20–30%, with much higher prevalence in adults with obesity (80–90%), diabetes (30–50%), and hyperlipidemia (90%)"(5).

Among the more affluent regions of China, the prevalence rate of non-alcoholic fatty liver disease (NAFLD) is approximately 15%(6). The number may decrease substantially if the poor rural populations where obesity is non-existence are also taking into account(7).

The exact causes of NAFLD aren't well understood. Some researchers suggested that certain risk factors such as long-term use of certain medications(8), genetic preposition(8), insulin resistance(8), high cholesterol(8) and triglycerides(8) in the blood, polycystic ovary syndrome(8), metabolic syndrome(8), obesity(8), and type 2 diabetes(8) are associated with the onset of the disease.

A legume is a plant in the family Fabaceae that fruit or seed of a plant.
On finding a potent ingredient for the treatment of liver diseases, researchers investigated the impact of legume intake, including green bean against the risk of nonalcoholic fatty liver disease (NAFLD.

According to the results of the valid and reliable food frequency questionnaire returned by 169 newly diagnosed patients with NAFLD and 803 controls participated in the study, greater intake of green peas was associated with a lower risk of NAFLD.

According to the adjusted models for higher dietary intake of legumes, 0.73 (0.64-0.84), 0.61 (0.46-0.78), and 0.35 (0.17-0.74), respectively.

In other words, legumes showed the highest effect compared to those of individual legume such as lentils, and beans.

Taken altogether, legume may be considered functional veggies for the prevention and treatment of NAFLD,  pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Legume intake and risk of nonalcoholic fatty liver disease by Bahrami A1, Teymoori F1, Eslamparast T2, Sohrab G2, Hejazi E2, Poustchi H3, Hekmatdoost A. (PubMed)
(2) Non-alcoholic Fatty Liver Disease (NAFLD)Treatment in Phytochemicals Perspective by Kyle J. Norton

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