Tuesday, 8 January 2019

Phytochemical Allicin, The Natural Anti High Blood Pressure Bioactive Ingredient

By Kyle J. Norton

Scientists may have found a bioactive ingredient which can normalize the blood pressure without inducing any side effects, according to studies.

Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

High blood pressure is a condition of abnormally high blood pressure, leading to the raising pressure in your heart.

If it stays high over time it can cause hardening and stiffening arterial wall,, a major risk factor of heart diseases.

The ideal blood pressure is more than 120 over 80 and less than 140 over 90 (120/80-140/90), according to the consensus.

Abnormal high blood pressure, depending on the how high of the numbers, patients may experience symptoms of a headache to a severe headache., fatigue, vision problems. However, in severe cases, high blood pressure can also induce chest pain, difficulty breathing, irregular heartbeat and confusion.

Untreated high blood pressure, epidemiologically can cause complications of retinopathy, lead to damage to the retinal or bleeding in the eye, blurred vision and complete loss of vision.

Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as damaging the kidney.

If you can control your diet, such as making changes to lifestyle, maintaining ideal weight and diet with low salt, you could do just fine without the drugs.

According to the hypertension clinical guideline from the National Institute for Health and Clinical Excellence (NICE) usefully recommends regular aerobic exercise and reduction of salt, alcohol, and smoking, and advocates ‘healthy, low-calorie diets' for ‘overweight individuals with raised blood pressure'".

This suggestion once again, highlighted that high blood pressure can be prevented by a change to a healthy lifestyle.

On finding a natural ingredient for the prevention and treatment of high blood pressure with no side effects, scientists at the Clinical Research Center looked into the antihypertensive effect of a popular garlic preparation containing 1.3% allicin at a large dose (2400 mg).

Nine patients with rather severe hypertension (diastolic blood pressure > or = 115 mm Hg) were included in the study.

Application of the preparation reduced the sitting blood pressure by 7/16 (+/- 3/2 SD) mm Hg at peak effect approximately 5 hours after the dose, with a significant decrease in diastolic blood pressure (p < 0.05) from 5-14 hours after the dose. 

No significant side effects were reported. The findings strongly indicate that this garlic preparation can reduce blood pressure.

Futhermore, in order to compare the antihypertensive effect of the different fractions of garlic, researchers investigated the hypotensive action of time-released garlic powder tablets (Allicor) vs regular garlic pills (Kwai).

84 men with mild or moderate arterial hypertension have participated in the study.

After an 8-week placebo treatment run-in phase, patients were randomized either to 600 mg Allicor (n=30) or to placebo (n=20) daily for 8 weeks. In addition, in the open-label branch, patients received either 2400 mg Allicor daily (n=18) or 900 mg Kwai daily (n=16).

Allicor treatment (600 mg daily) resulted in a reduction of both systolic and diastolic blood pressures by 7.0 mm Hg (95% confidence interval (95% CI): 5.3-8.7) and 3.8 mm Hg (95% CI: 2.7-4.8), respectively. Increasing the Allicor dosage to 2400 mg daily did not provide any additional benefit.

Treatment with Kwai resulted in the same decrease in systolic blood pressure (5.4 mm Hg, 95% CI: 1.9-8.8) as that seen with Allicor, but no decrease in diastolic blood pressure.

In the depth analysis, researchers found that different effects of Allicor and Kwai on diastolic blood pressure may be associated with the prolonged action of Allicor.

Dr. Sobenin IA, wrote in the final report, "The results of this study show that time-released garlic powder tablets are more effective for the treatment of mild and moderate arterial hypertension than are regular garlic supplements".

Taken altogether,. allicin, a bioactive compound of garlic may be used for the prevention and treatment of high blood pressure with no side effects

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Can garlic lower blood pressure? A pilot study by McMahon FG, Vargas R.(PubMed)
(2) Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension by Sobenin IA, Andrianova IV, Fomchenkov IV, Gorchakova TV, Orekhov AN. (PubMed)
(3) Hypertension and lifestyle modification: how useful are the guidelines? by Rachel Nicoll. (PMC)

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