Scientists may have found a natural remedy for the prevention and treatment of chronic kidney disease with no side effects, according to studies.
The renoprotective effect is protection against anything that can cause the harm to the kidney.
Chronic kidney disease, also known as chronic kidney failure, is a condition of gradual loss of kidney function.
It has been used in traditional Siddha and Ayurvedic doe the treatment of the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chicken pox, etc.
Besides the main ingredient andrographolides, giving the plant a bitter taste, other ingredients of herbal Andrographis include diterpene lactones, such as neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoinds viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
With an aim to find a natural compound or whole herb for the treatment of reno disease with no side effects, researchers examined the anti-renal failure activity of A. paniculata.
The study included Male Wistar albino rats divided into three groups: normal control, gentamicin control, and an aqueous extract of A. paniculata (200 mg/kg, per oral (p.o.))-treated.
The nephrotoxic model was induced by gentamicin (80 mg/kg, intraperitoneal (i.p.)).
Taken altogether, herbal Andrographis may be considered a functional remedy for the prevention of kidney damage caused by oxidative stress and reno failure and combined with the primary therapy for the treatment of kidney diseases with no side effects, pending to the confirmation of large sample size and multicenter human study.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Renoprotective effects of Andrographis paniculata (Burm. f.) Nees in rats by Singh P, Srivastava MM, Khemani LD.(PubMed)
(2) Prevention of cadmium bioaccumulation by herbal adaptogens by Bharavi K, Reddy AG, Rao GS, Kumar PR, Kumar DS, Prasadini PP.(PubMed)
(3) The significance of diet in chronic kidney disease by Chaudhary Muhammad Junaid Nazar. (PMC)