Saturday, 30 December 2017

Herbal Therapy: Green Tea in Protection Against Chronological and Photo Aging

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)

Although no one can avoid aging, the process can be slow down. Green tea may have a potential and positive effect in delay the process through its anti aging phytochemicals, some scientists suggested.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

The investigation of green tea properties in anti aging effect was found to associate many different mechanisms involved expression of some major polyphenols.

According to the investigation of  the experiment of 45 male mice model divided into 5 groups  induced aging through injection of d-galactose in the period of 8 weeks in compared to positive control fed with Vitamin C (VitC), mice treated  with green tea, bioactive Epigallocatechin gallate(EGCG) once a day by subcutaneously inject after 5h of injecting d-galactose exerted a antioxidant effect in improved over all skin condition and whole structure of skin in compared to positive control at the end of study.

Further analysis also found that the chemical constituents of green tea inhibited the over production of osidative stress caused by injection of d-galactose through neutralized ROS insults to maintain good dermal health.

Interestingly, in compared to control, green tea EGCG also increased expression of epidermal growth factor in stimulated skin growth at the cellular level and increase collagen production in protect skin against aging senility.

Moreover, the evaluated characteristics of human skin and how photo-aging (extrinsic aging) occur via the impact of ROS production by cascade signaling pathways indicated that administration of green tea extracts (GTEs) protects the affect of aging skin through inhibited cutaneous erythema induced of redness of the skin, thickening of the epidermis involved over expression of CK5/6 in promoted cutaneous neoplasms, a new and abnormal growth of skin tissue and cytokeratin(CK16) in induction of expression in abnormal skin epithelial patterns.

In deed, the expression green tea also showed a strong implication in reduced matrix metalloproteinases 2-9 (MMP-2, MMP-9) activities in elevated skin changes and depletion of CD1a(+) LCs in induction of skin inflammation, caused by UVR application

In chronological (intrinsic) aging, administration of polyphenols, which are secondary plant metabolites also found to protect against skin aging through exhibition of antioxidant and anti-inflammatory effects, according to the existing literature, linking skin aging and the ability of polyphenols as regulatory elements with function in maintained skin homeostasis.

Dr. Davinelli S, said at end of study, "Polyphenols exert their influence mostly through their antioxidant and anti-inflammatory effects, thereby abrogating collagen degradation and/or increasing procollagen synthesis".

Finally, in the 33 healthy Asian subjects, all men enrolled after consent in a placebo-controlled comparative study with a split face design with one group applied multiple emulsions with green tea and the second group applied multiple emulsions with lotus extract, while a third group applied a multiple emulsion with a combination of both extracts, once daily over the 60-day treatment researchers found that all groups show a significant improvement on skin roughness (SEr), scaliness (SEsc), smoothness (SEsm), and wrinkling (SEw). In compared to other 2 groups, green tea and lotus combined in multiple emulsions brought a superior synergistic anti-aging effect..

Dr. Mahmood T, the lead author, after taking into account of other con founders, said, "diverse anti-oxidant constituents in both plants have a potential influence on skin surface parameters, thus indicating these plants as the future of new anti-agingproducts".

Taken together, green tea bioactive polyphenols may be considered as a functional food used as topical or oral injection to delay skin aging process through over expression antioxidant in improved in both chronological (intrinsic) and photo-aging (extrinsic) aging.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Combined topical application of lotus and green tea improves facial skin surface parameters by Mahmood T1, Akhtar N.(PubMed)
(2) Protective effects of green tea extracts on photoaging and photommunosuppression by Li YH1, Wu Y, Wei HC, Xu YY, Jia LL, Chen J, Yang XS, Dong GH, Gao XH, Chen HD.(PubMed)
(3) Anti-skin-aging effect of epigallocatechin gallate by regulating epidermal growth factor receptor pathway on aging mouse model induced by d-Galactose by Chen J1, Li Y2, Zhu Q1, Li T1, Lu H1, Wei N2, Huang Y1, Shi R2, Ma X3, Wang X4, Sheng J5.(PubMed)
(4) Cytoprotective Polyphenols Against Chronological Skin Aging and Cutaneous Photodamage by
Davinelli S, et al. Curr Pharm Des. 2017(PMC)

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