Intake of beet juice may have a reduced effect of inflammation through suppressing production of pro inflammatory cytokines produced by immunity.
Inflammation is the reaction of immune system in protected our body against foreign invasion cause of infection or tissues damage.
Beet, best known as the beetroot or garden beet is a perennial plant with leafy stems growing to 1–2 m tall, belonging to the amaranth family,
Intake of raw beet juice (RBJ) and cooked beet (CB) on BP of hypertensive subjects, showed a significant improvement of inflammation through regulating the cell signal protein in initiation of systemic inflammation involved in acute phase of inflammatory cytokine tumor necrosis factor alpha (TNF-α) and reducing high-sensitivity level of C-reactive protein (hs-CRP) which have a major effect in the onset of cardiovascular risk in both tested groups.
Although the reduced blood pressure is not sustainable in tested subjects after creasing intake of raw beet juice (RBJ) and cooked beet (CB), the improvement of endothelial function as a result of the presence of nitric oxide and systemic inflammation during the test are remarkable.
Endothelial dysfunction is a major risk factor of cardiovascular disease and precedes the development of atherosclerosis.
In muscle damage following a marathon of 30 recreationally active males, using a double blind, independent group design with doses of beetroot juice (H-BT; 250 ml), a lower dose of beetroot juice (L-BT; 125 ml), or an isocaloric placebo (PLA; 250 ml) immediately (×3 servings), oral administered beet juice groups, showed a faster recovery of muscle damage at 48 hours in compared control.
Further analysis, application of beetroot juice in any dose enhanced over expression of antioxidants induced recover of muscle damage not only was attributed to the juice function in reduced high-sensitivity level of C-reactive protein (hs-CRP) but also increased modulation of enzyme creatine kinase (CK) responsible in expression by various tissues and cell types during muscle damage.
Neutrophils is a type of immune cells released to site of infection by immunity. Over expression of neutrophils normally are an indication of acute infection.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Improvement of hypertension, endothelial function and systemic inflammation following short-term supplementation with red beet (Beta vulgaris L.) juice: a randomized crossover pilot study by Asgary S1, Afshani MR2, Sahebkar A3,4, Keshvari M1, Taheri M5, Jahanian E6, Rafieian-Kopaei M7, Malekian F8, Sarrafzadegan N1.(PubMed)
(2) The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise by Clifford T1, Bell O2, West DJ2, Howatson G2,3, Stevenson EJ2.(PubMed)