Beet may have a potential effect as antioxidants in reduced free radical and oxidative stress expression through its chemical constituents, some scientists suggested
Antioxidants are the set of substances with inhibited oxidative function
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the joint study lead by the Istanbul Technical University, fresh red beetroot and beet roots products contain several major antioxidants with efficacy different, depending to total antioxidant capacities (TAC)(total phenolic (TP) and total flavonoid (TF) contents and individual).
In Lactobacillus paracasei 0920 (FBJ) on carcinogen induction of aberrant crypt foci (ACF), the abnormal tube-like glands in the lining of the colon and rectum in rat colon by 2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) administrated intragastrically at a dose of 10 μg/day, every day of the experiment, rats fed with beetroot juice showed a significant improvement of cytotoxic and genotoxic effects through increased the antioxidant status of serum from 40% to 66% depending on the fraction.
In other words, oxidative stress induced production of toxins and toxic chemical agents which may alternate DNA transcript were inhibited by phytochemicals in beet juice.
2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) is a toxic chemical formed in condensation of creatinine found in muscle meats, with amino acids in high temperature,
in treatment of diseases associated with oxidative stress.
Additionally, in a male Wistar rat model of oxidative stress induced by N-nitrosodiethylamine (NDEA) and carbon tetrachloride (CCl(4)), group fed with beetroot juice per os, 8 mL/kg/day for 28 days, and a single i.p. dose of the xenobiotics: 150 mg/kg NDEA or 2 mL/kg CCl(4) and xenobiotics only group, treatment group showed a partial recovery in the activity of glutathione peroxidase and glutathione reductase, by 35% and 66%, respectively.
Glutathione peroxidase (GPx) with peroxidase activity is an antioxidant with function to protect the organism from oxidative damage.
The activity of glutathione reductase is a cellular antioxidant with function to protect the organism against xenobiotics.
Particularly, the levels of Superoxide dismutase activity against oxidative stress induced formation of inflammation also increased by 3-fold in compared to non juice treatment group.
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Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Home-Processed Red Beetroot (Beta vulgaris L.) Products: Changes in Antioxidant Properties and Bioaccessibility by Guldiken B1, Toydemir G2, Nur Memis K3, Okur S4, Boyacioglu D5, Capanoglu E6.(PubMed)
(2) Protective effect of lactofermented red beetroot juice against aberrant crypt foci formation, genotoxicity of fecal water and oxidative stress induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in rats modelm by Klewicka E1, Nowak A, Zduńczyk Z, Juśkiewicz J, Cukrowska B.(PubMed)