Herbal Burdock, The Functional Herb Which Protects Skin Against Aging Caused by Reactive Oxidative Species (ROS)

Kyle J. Norton (Master of Nutrition, All right reserved)

Herbal Burdock may process a profound and positive effect in inhibited free radicals activity in induction of early onset of natural aging, some scientists suggested.

Burdock is plant in the group of biennial thistles, genus Arctium,belongings to the family Asteraceae, native to the Euro.

The herb has been used over thousand of years in China and other traditional herbal medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.

A free radical is any atom or molecule that has a single unpaired electron in an outer shell and highly reactive to react with other cell, which in turn, causes oxidative damage to the enzymes, other protein,.... unsaturated fatty acid.

Prolonged over expression of free radical were found to cause widespread damage through domino's  chain reaction auto-catalytically after attacking the lipid bilayers of the cell walls.

Truly, epidemiological studies strongly suggested that reactive oxygen and nitrogen species (ROS/RNS) existed as radicals or nonradicals, as well as reactive sulfur species and reactive carbon species, play a major role in aging processes.

Dr. Wölfle U, the lead scientist in the examine the effect of ROS in induction of skin aging said, " When RMS concentrations exceed a certain threshold, cell compartments and cells are injured and destroyed" and " Endogenous physiological mechanisms are able to neutralize RMS to some extent, thereby limiting damage. In the skin, however, pollutants and particularly UV irradiation are able to produce additional oxidants which overload the endogenous protection system and cause early aging, debilitation of immune functions, and skin cancer".

Some researchers suggested that unhealthy diet with low nutrition high in advanced glycation end products (AGEs) may also contribute to oxidation induced early aging process.

The Chemical Ingredients of Herbal Burdock include
Carbonated water, sugar, manloid colourings, phosphoric acid, citric acid and a good amount of dietary fiber, calcium, potassium, and amino acids and chemicals compounds of guaianolide, arctinone, arctinal, methyl arctate，11-tridecadien-3，5，7，9-tetraynde-hydrocostus lactone，dehydrodihydrocostus lactone, 3-octenoic acid, 3-hexenoic acid etc.

In the study of the activity of superoxide dismutase (SOD) and the content of Malondialdehyde (MDA) and lipofuscin in the tissues of the liver, brain and blood serum of the lab rats at the 30 days after feeding with the Niubanggen decoction, researchers found that

* Levels of SOD in the liver tissue and blood serum were improved substantiallyin decoction treat rats

* Levels of the content of MDA in the brain tissue and blood serum were lower in compared to baseline.

* Levels of lipofuscin were also dropped significantly.

These results suggested that herbal burdock exerts strong anti-aging effects through activating antioxidant of the host in inhibited ROS in induction oxidative stress through expression of biomarkers of SOD and MDA and lipofuscin.

Herbal burdock antioxidant activity in the differentiation of 23 distinct herbal medicine was found to process anti-elastase activities up to 51% in prevention of destruction of elastic fiber.

Furthermore, in the review of the therapeutic effects of the active compounds presented in the different botanical parts of burdock, researchers at the The Hong Kong Polytechnic University, found that the root of burdock containing active ingredients "detoxify" blood in terms of TCM and promote blood circulation to the skin surface, improving the skin quality/texture and curing skin diseases like eczema.

However, burdock may induce contact dermatitis and other allergic/inflammatory responses, the University continued.

Taking altogether, function herb burdock processes bioactive ingredients which protect the skin against aging and disease through its antioxidants activity in inhibited over expression of free radicals.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

References
1. An experimental research into the anti-aging effects of Radix Arctii Lappae, by Liu S, Li Y, Li S, Luo M, Liu X.(PubMed)
2. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants.
Thring TS, Hili P, Naughton DP.(PubMed)
4. A review of the pharmacological effects of Arctium lappa (burdock)" by Chan YS, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW., (PubMed)
(5) Sugar Sag: Glycation and the Role of Diet in Aging Skin by Nguyen HP1, Katta R(PubMed)