Sunday, 30 September 2018

Infectious Diseases: Green tea, The Beverage Kills Bacterial Staphylococcus and Streptococcus That Cause Cellulitis

Kyle J. Norton 

Green tea may have a therapeutic and positive effect of reducing risk and treatment of cellulitis, some scientists suggested.

The results of the investigation were evaluated by numbers of respectable institutes, including the University of Indonesia and Mashhad University of Medical Sciences and published online in some medical literature databases including PubMed.

Cellulitis is a common and serious bacterial skin infection that affects the deep layer of skin, caused mostly by Staphylococcus and Streptococcus bacteria, inducing symptoms of a red, swollen skin rash (usually on the lower legs or arms) that feels tender and hot.

The skin infectious disease can appear anywhere in the body, however, in most cases, it affects the skin of the lower legs.

Some researchers suggested that people with a weakened immune system such as age population and intake of immune suppressive drugs and obesity are most likely to develop cellulitis.

As always, most cases of cellulitis are treated with antibiotics in a period of 5-10 days. Please make sure that you discuss the side effects of the medicine with your doctor.

Although it is rare, some people with severe cellulitis that experience severe symptoms of high fever or vomiting and fails to respond to treatment.

Recurrences of cellulitis may require antibiotics that are given by IV.

Green tea is a precious drink processed numbers of health benefit known to almost everyone in Asia and the Western world.

In the searching of natural antibiotics against skin infection such as cellulitis, by reviewing some plants for the treatment of skin diseases taken place during the past 17 year using the of plants is as old as the mankind, researchers found that green tea with abundant polyphenols, epigallocatechin gallate exerts a strong effect as antioxidants to reduce the risk of skin diseases, including tumors, herpes, and cellulitis. 

According to the National Center for Complementary and Alternative Medicine, application of EGCG also demonstrated a potential in rejuvenated old skin cells.

Further analysis of green tea catechins, the major green tea polyphenols, exhibited antimicrobial activity against resistant pathogens in induction of skin infection, including cellulitis, researchers at the Mashhad University of Medical Sciences conducted a study to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) values of different agents against bacterial strains, through assessing the interactions of green tea extract, epigallate catechin, epigallocatechin gallate, two types of methylxanthine, caffeine, and theophylline with gentamicin against standard and clinical isolates of Staphylococcus aureus (S. aureus) and the standard strain of Pseudomonas aeruginosa (P. aeruginosa).

According to the final phase of the experiment, researchers indicated that
*The MICs of gentamicin against bacterial strains were in the range of 0.312 - 320 μg/mL and the MIC values of both types of catechins were 62.5 - 250 μg/ mL.

* Green tea extract showed insufficient antibacterial activity when used alone 

* Methylxanthines had no intrinsic inhibitory activity against any of the bacterial strains tested.

* When green tea extract and catechins were combined with gentamicin, the MIC values of gentamicin against the standard strains and a clinical isolate were reduced, and synergistic activities were observed (FICI < 1). 

* A combination of caffeine with gentamicin did not alter the MIC values of gentamicin.

The results of all comparison after taking into account of other co and confounders revealed that green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of S. aureus and standard P. aeruginosa strains",  Dr. Fazly Bazzaz BS, the lead author said.

Moreover, the evaluate the antibacterial activity of the Indonesian water soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus (S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa) also lends a support of the above differentiation.

According to the University of Indonesia,
* The inhibition zone diameter of green tea extracts for S. aureus ATCC 25923 and MRSA were (18.970 ± 0.287) mm, and (19.130 ± 0.250) mm respectively. 

* While the inhibition zone diameter for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were (17.550 ± 0.393) mm and (17.670 ± 0.398) mm respectively. 

* The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 µg/mL and 400 µg/mL, respectively.

* Finally, the MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were 800 µg/mL, and 800 µg/mL, respectively.

Taken together, green tea and its bioactive compounds may be considered as a functional food for reduced risk and treatment of cellulitis caused by Staphylococcus and Streptococcus bacterial infection.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Plants used to treat skin diseases by Nahida Tabassum and Mariya Hamdani(PMC)
(2) Effect of Catechins, Green tea Extract, and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria by Fazly Bazzaz BS1, Sarabandi S2, Khameneh B3, Hosseinzadeh H4.(PubMed)
(3) Antimicrobial activity of green tea extract against isolates of methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa by Radji M1, Agustama RA, Elya B, Tjampakasari CR.(PubMed)

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