Thursday, 13 September 2018

Chamomile, The Herb Which Processes Benzodiazepine-Like Hypnotic Activity For Pain, Anxiety,... and Sleep Disorder With No Adverse Effects, Scientists Say

By Kyle J. Norton, Master of Nutrition


"Let foods be your medicine and let medicines be your food", using foods as medication has been a dream of many scholars and scientists over past many centuries.

 In order to achieve these, consumption of whole food medicine must be accompanied by moderated exercise, change of diet and life style.

Chamomile, the most frequently used medical plant may be next generation of whole herb to act as sedative agent to treat pain, anxiety,...... and sleep disorder.

Sedation is a action that induces calm or sleep by using medicine, drugs, or substances to suppress the activity of central nervous system.

Over dose of sedative substances can be fatal.

Medicine such as placidyl, ethchlorvynol. a mild sedative-hypnotic drug used for treatment may be effective, but they can cause serious side effects such as skin condition, such as skin rash or hives dizziness,...... nervousness and restlessness.
In some cases, patients overdose with sedative drugs can also cause darkening of urine, pale stools, yellow eyes,....skin easily bled or bruised, confusion, change of vision or (continuing),..... and double vision.

Sleep disorder is a problem of sleeping. classification of sleep disorder deepening to types of condition includes, insomnia, a problem of falling and staying asleep, excessive daytime sleepiness, sleep-disruptive behaviors,.... and sleep rhythm problem.

According to statistic, between 50-70 million US adults have a sleep disorder.

Chamomile is also known as camomile, common name of many species daisy-like plants in the family Asteraceae, 

The herbal medicine has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.

In a quasi-experimental clinical trial, included 77 cases of elderly hospitalized in nursing homes, using random continuous sampling by divided into intervention group received 400 mg oral capsules of chamomile twice daily, after lunch and after dinner for 4 weeks. and control groups received nothing to test the efficacy of chamomile in sleep disorder, researchers showed that oral administration of chamomile extract has sedative properties in sleep quality in compared to control.

These results were observed by analyzing the Pittsburgh Sleep Quality Index questionnaire in compared to no different of the mean score of sleep quality both experimental and control groups before experiment, the mean score of sleep quality was a significant difference between experimental and control groups after 4 weeks.

Moreover, in a triple blind clinical trial performed on 114 eligible women at Ommolbanin Hospital in Mashhad, Iran in 2014, randomly assigned to two groups using random blocks. After delivery, 
* mothers in the intervention group are received 0.5 g of prescribed chamomile

* Mothers in the control group are given placebo cream on the stitch twice a day lasting ten days.

At the end of the study, researchers found that mothers received chamomile cream is found to reduce episiotomy pain sedately in primiparous women in compared to control.

Additional differentiation and after taking into account of other co con founders, researchers also discovered, although there are no difference before and 12 hours and the first day after delivery. on the seventh, tenth and fourteenth day after delivery according to McGill mean (SD) pain score,  experimental group was 11.36, 4.44 and 7.16 in compared to control group of 14.88, 7.41 and 9.96 respectively.


Dr. McKay DL said, " Chamomile has moderate antioxidant and antimicrobial activities, and significant antiplatelet activity Animal model studies indicate potent antiinflammatory action, some antimutagenic and cholesterol-lowering activities, as well as antispasmotic and anxiolytic effects" and "(Unfortunately) However, human studies are limited, and clinical trials examining the purported sedative properties of chamomile tea are absent."

In fact, in the investigated hypnotic activities of chamomile and passiflora extracts using sleep-disturbed model rats, researcher at the Okayama University insisted, chamomile extract at a dose of 300 mg/kg exerted significantly decrease sleep latency.

The study also suggested, chamomile extract is a herb having benzodiazepine-like hypnotic activity.

Taking altogether, Chamomile may be helpful to aid pain, calm and sleep through its sedative effects, but intake of correct amount should only be given by qualified herbalist



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Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Investigation effect of oral chamomilla on sleep quality in elderly people in Isfahan: A randomized control trial by Abdullahzadeh M1, Matourypour P2, Naji SA1.(PubMed)
(2) The Effect of Chamomile Cream on Episiotomy Pain in Primiparous Women: A Randomized Clinical Trial by Aradmehr M1, Azhari S2, Ahmadi S3, Azmoude E4.(PubMed)
(3) Hypnotic activities of chamomile and passiflora extracts in sleep-disturbed rats by Shinomiya K1, Inoue T, Utsu Y, Tokunaga S, Masuoka T, Ohmori A, Kamei C.(PubMed)