Wednesday, 14 February 2018

Food Therapy: Fennel In Attenuated Risk, Progression and Treatment of Intestinal Dysbiosis

Kyle J. Norton

Fennel may have a potential and therapeutic effect in reduced risk, progression and treatment of gastrointestinal dysbiosis, some scientists suggested.

Dysbiosis is most commonly gastrointestinal tract disorder, caused by imbalanced microbiota in the gastrointestinal tract particularly in the small intestines.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.

In the investigation of the effect of some herbal essential oil in risk of dysbiosis, researchers found that essential oil isolated from fennel exerts lesser inhibited function in reduced concentration of the growth of potential pathogens in compared to isolation of herbal Carum carvi, Lavandula angustifolia, Trachyspermum copticum, and Citrus aurantium var. amara without inducing any adverse effects.

Further analysis also suggested that ingestion of fennel essential oil although decrease levels of bad microbacteria concentration, they do not contribute to a substantially detrimental impact on beneficial members of the microflora.

The above differentiation was supported by the joint study conducted by the Scientific Board Member of Islamic Azad University, on 180 day-old broiler chicks to test the effect of composition of Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fenne) on antimicrobial activity of gut micro flora traits.

Application of the composition to samples chick randomly assigned to groups fed with control diet (without additives), diet accompanied with 2 mentioned mixed powder plants (0.5% of total diet), diet with TF mixed powder plant and diet with FV mixed powder plant, at the end of the experiment, demonstrated a significant improvement of balance of the gastrointestinal microflora, through expression of increased average daily feed intake (ADFI), average daily gain (ADG).

Additionally, the efficacy of the composition also decreased the concentration of number of G- bacteria (NGB), number of Coli form bacteria in compared to the sample taken before the experiment.

In deed, Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fennel) treated group displayed an enormous anti antimicrobial activity of gut in compared to the control group.

In  tested porcine gut, anethole, the bioactive compound found in essential oil isolated from fennel displayed a substantial  anti microbial activity against commensal and pathogenic bacteria, through inhibited the chloride secretion with function in major determinant of mucosal hydration throughout the gastrointestinal tract, induced by 5-HT metabolic signaling of gut microbes  and theophylline adverse effect in induction of gut disorder.

At dose of 0.5 mmol/L, anethole exerted a protective effect against micro imbalance in initiated gastrointestinal disorder by inhibition of excessive chloride secretion.

Taken together, the information finding suggested that fennel and its bioactive compound anethole may be considered as a function herb for reduced risk, progression and combined with standard medicine for treatment of  intestinal dysbiosis, without inducing intolerant side effects.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study by Hawrelak JA1, Cattley T, Myers SP.(PubMed)
(2) Effects of fenugreek and fennel seeds on growth performance and reducing the population of gut micro flora in broiler chicks [2010] by Kalantar, M.,Dakhili, M.,(PubMed)
(3) EFFECT OF THE ESSENTIAL OILS THYMOL, E-ANETHOLE AND ECINNAMALDEHYDE ON ACTIVE NUTRIENT ABSORPTION AND STIMULATED CHLORIDE SECRETION IN THE ISOLATED PIG GUT, Chapter 5 by JORIS MICHIELS

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