Carrots may have a profound and positive effect in reduced risk, progression and treatment of breast cancer, some scientists suggested.
Carrot, a root vegetable with orange color is a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C
In the review of carrot fractions' anticancer activities in vitro and in vivo, researchers found that pentane/diethyl ether (50:50) isolated from carrot express a significant anti cancer activity against various tumors, including on lung, skin, breast and glioblastoma cancer cell.
Interestingly, injection of F1 and F2 in MDA-MB-231 cells did not significantly reduce the level of phosphorylated Erk and phosphorylated Akt protein in induction of cancer cellular process involved cancer cell proliferation, differentiation, and survival.
Moreover, observation of combined treatment with wortmannin, a potent PI3K inhibitor and F1 or F2 fraction revealed that two drugs work on different pathways in the synergistically inhibitory effect on cell survival.
The above differentiation were supported by the National Institute of Environmental Health Sciences in estimate nutrients intake in nine questions on food and supplement in a population-based case-control study of breast cancer risk conducted in Maine, Massachusetts, New Hampshire, and Wisconsin in 1988-1991 with data for 3543 cases and 9406 controls.
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Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Daucus carota Pentane/Diethyl Ether Fraction Inhibits Motility and Reduces Invasion of CancerCells by Zgheib P1, Daher CF, Mroueh M, Nasrallah A, Taleb RI, El-Sibai M.(PubMed)
(2) Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby WN, Mroueh M, Bodman-Smith K, Mansour A, Taleb RI, Daher CF, El-Sibai M1.(PubMed)
(3)Intake of carrots, spinach, and supplements containing vitamin A in relation to risk of breast cancer by Longnecker MP1, Newcomb PA, Mittendorf R, Greenberg ER, Willett WC.(PubMed)