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By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
What is Candida Albicans
Candida albicans are members of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract. In fact, under normal circumstances, Candida albicans that do not cause harmful effects, but overgrowth result in candidiasis. Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1). According to joint study, in many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased Candida resistance toward antifungal agents.
In Traditional Chinese Medicine
In traditional Chinese medicine, candidiasis is defined as a malfunction of the Triple Burner-related condition due to spleen and stomach disorder(401), causing excess fluid or phlegm in our system(402), weakening immune system(403)(402), leading to damp heat accumulates in the Lower, Middle and Upper Burner causes of candidiasis(401).
After cleansing the body with the above herbs, repairing the damage and restoring the balance are vital to prevent the reoccurring of the pathological factors in TCM.
1. Ren Shen (Radix Ginseng)
Ren shen is aslo best known as Ginseng, a slow-growing plant, belonging to the Panax genus in the family Araliaceae. The smells aromatic, tastes sweet and slightly warm herb(541) has been used in TCM as anti cancer(542)(543), anti aging(544)(545) medicine and to enhance central nervous (546)(547), immune(548)(549), and circulatory system(549)(551) as it tonifies original qi, spleen, lungs and enhances the generation of body fluids by promoting the function of lung and spleen channels(541).
According to China Academy of Chinese Medical Sciences formula ginseng-sanqi extract (GSE) showed to tonify qi and activating blood circulation in promoting endothelial proliferation(an increase in vascular endothelial cells needed for the growth of new or existing blood vessels) and angiogenesis( a process of growing new blood vessels form from pre-existing vessel), through enhancing the expression of angiogenesis signaling proteins (VEGFR-2, Ras, MAPK)(552).
2. Bai Zhu (Rhizoma Atractylodis Macrocephalae)
Bai zhu is also known as Bighead atractylodis rhizome, a genus Atractylodis, belonging to the family Asteraceae. The aromatic, acrid, and sweet herb(553) has been used in TCM as antioxidant(554)(555), to treat liver diseases(556), liver cancer(558)(559), Meniere's disease(560), intestinal diseases(561), chronic back pain(562), acute infection of intestine(563) as it regulates the functions of liver and spleen, benefiting qi, and nourishing blood(557) by enhancing the functions of spleen and stomach channels(553).
3. Fu Ling (Sclerotium Poriae Cocos)
Fu ling is also known as Poria or china root, is a fungus in the genus Wolfiporia, belonging to family Polyporaceae. The sweet and neutral herb has been used in TCM as inflammatory(566)(567), diuretics(569)(570), anticancer(572)(573), antioxidant(573)(574) and anti-fungal and anti-bacterial(575)(571) agents, and to treat headache(568), cardiovascular diseases(576), neuro disorders(577) insomnia(578), loss of appetite(564) as it strengthens spleen and calms the mind by clearing away the stomach-heat, purging the heart fire, strengthening the spleen and tonifying the kidney(565) through enhancing the function of heart, spleen, lung, kidney channels(564).
4. Chen Pi (Pericarpium Citri Reticulatae)
Chen Pi, also known as Tangerine Peel, is the skin of is an orange-coloured citrus fruit, belonging to the genus Citrus in the family Rutaceae. The bitter, acrid, warm herb has been used in TCM as antioxidant(580)(582), antimicrobial(579)(580)(581) and cytotoxic(580)(583) agents and to improve digestive functions(584), stop bleeding(585), increase blood pressure(585) and stimulate blood vessels(585) as it regulates qi and the middle burner, dry dampness and transform phlegm(586) by promoting the functions of lung and spleen channels(585).
5. Ban Xia (Rhizoma Pinelliae Ternatae)
Ban xia is also known as Pinellia Tuber, a genus of Pinellia, belonging to the family Araceae and native to China. The acrid, warm, toxic herb(587)been used in TCM as anti nephritis(587)(592), anti cancer(589)(590), anti diabetic(591), anti hypercholesterol(592(598)), expectorant(593) and anti convulsant(594) agents and to facilitate gastric disorders(588), get rid of phlegm(597) and induce calming(596) as it dries dampness(587), and tonifies middle burner that aids digestion(595) by enhancing the functions of lung, spleen and stomach channels(587).
According to Nanjing University, banxia also exhibited anti microbial activities, including candida albicans, through its phytochemicial Pinelloside(596). crude extracts of 7 spcies, including sha ren
6. Sha Ren (Adenophora verticillata, Fisch)
Sha Ren is also known as cardamom seeds, the tree is belong to the genus Elettaria and Amomum in the family Zingiberaceae, native to in Asia and Australia. The acrid, warm and nontoxic(599) herb
has been used in TCM to treat digestive tract disorders(600)(601), such as bloating, stomach ache, nausea, vomiting and lack of appetite and gastric ulcer, as it transforms dampness(604), stimulate movement of qi and warms the middle burner(603) by promoting the functions of kidney, spleen and stomach channels(599).
According to University of Medical Sciences, showed effectively 100% inhibition of the pathogen mycelial growth, through it s anti fungal effects(602), in vitro.
7. Mu Xiang (Radix Aucklandiae)
Mu Xiang is also known as costus root, a genus is a genus Saussurea in the family Asteraceae, native to cool temperate helps to and arctic regions of Asia, Europe, and North America. The acrid, bitter and warm herb(605) has been used in TCM as anti microbial(606), anti diabetic(607) and, anti gastric ulcer(611) anti cancer(608)(609) agents and to treat digestive disorders(612), such as pain in the abdomen, diarrhea, vomiting caused by weak digestion, digestive tract infection(606) and yeast infection(606) as it enhances movement of qi, regulates the middle burner(612), dissolves damp-heat(610) by promoting the functions of gallbladder, large intestine, spleen, stomach channels(603).
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(1) Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance by Krcmery V1, Barnes AJ.(PubMed)
(2) Pathogenicity and drug resistance in Candida albicans and other yeast species. A review by Mishra NN1, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R.(PubMed)
(3) Multidrug resistance in yeast Candida by Prasad R1, Kapoor K.(PubMerd)
(4) New evidence that Candida albicans possesses additional ATP-binding cassette MDR-like genes: implications for antifungal azole resistance. by Walsh TJ1, Kasai M, Francesconi A, Landsman D, Chanock SJ.(PubMed)
(5) Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.by Sanglard D1, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.(PubMed)
(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
(7) The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms by Ibrahim NH1, Melake NA2, Somily AM3, Zakaria AS4, Baddour MM5, Mahmoud AZ6(PubMed)
(8) Antifungal drug resistance in pathogenic fungi. by Vanden Bossche H1, Dromer F, Improvisi I, Lozano-Chiu M, Rex JH, Sanglard D.(PubMed)
(9) The genetic basis of fluconazole resistance development in Candida albicans by Morschhäuser J1.(PubMed)
(10) A proteomic approach to understanding the development of multidrug-resistant Candida albicans strains by Kusch H1, Biswas K, Schwanfelder S, Engelmann S, Rogers PD, Hecker M, Morschhäuser J.(PubMed)
(541) Ren shen(Complementary and Alternative Healing University)
(542) Anti-proliferative effect of ginseng saponins on human prostate cancer cell line by Liu WK1, Xu SX, Che CT.(PubMed)
(543) Stereoisomer-Specific Anticancer Activities of Ginsenoside Rg3 and Rh2 in HepG2 Cells: Disparity in Cytotoxicity and Autophagy-Inducing Effects Due to 20(S)-Epimers by Cheong JH1, Kim H, Hong MJ, Yang MH, Kim JW, Yoo H, Yang H, Park JH, Sung SH, Kim HP, Kim J.(PubMed)
(544) Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging by Zhu J1, Mu X1, Zeng J2, Xu C1, Liu J1, Zhang M1, Li C1, Chen J3, Li T3, Wang Y1.(PubMed)
(545) Fermenting red ginseng enhances its safety and efficacy as a novel skin care anti-aging ingredient: in vitro and animal study by Lee HS1, Kim MR, Park Y, Park HJ, Chang UJ, Kim SY, Suh HJ.(PubMed)
(546) Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging by Zhu J1, Mu X1, Zeng J2, Xu C1, Liu J1, Zhang M1, Li C1, Chen J3, Li T3, Wang Y1.(PubMed)
(547) Neuroprotective effect of water extract of Panax ginseng on corticosterone-induced apoptosis in PC12 cells and its underlying molecule mechanisms by Jiang Y1, Li Z1, Liu Y1, Liu X1, Chang Q1, Liao Y1, Pan R2.(PubMed)
(548) Immune system effects of echinacea, ginseng, and astragalus: a review by Block KI1, Mead MN.(PubMed)
(549) Ginseng, the 'Immunity Boost': The Effects of Panax ginseng on Immune System by Kang S1, Min H.(PubMed)
(550) A review on the medicinal potentials of ginseng and ginsenosides on cardiovascular diseases by Lee CH1, Kim JH2.(PubMed)
(551) Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications by Kim JH1.(PubMed)
(552) [Effect of ginseng-sanqi extract on the Ras associated signal proteins].[Article in Chinese] by Tian W1, Lei Y, Zhu LQ.(PubMed)
(553) Bai zhu(Complementary and Alternative Healing University)
(554) Antioxidant activity of qizhu tang by Wang XJ1, Feng P.(PubMed)
(555) Antioxidant potential of qizhu tang, a chinese herbal medicine, and the effect on cerebral oxidative damage after ischemia reperfusion in rats by Xuejiang W1, Ichikawa H, Konishi T.(PubMed)
(556) Compositions for protecting liver, or for preventing or treating liver fibrosis or cirrhosis US 20080260870 A1
(557) Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS by Cao G1, Li Q2, Cai H3, Tu S4, Cai B1.(PubMed)
(558) Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells byYe Y1, Wang H, Chu JH, Chou GX, Chen SB, Mo H, Fong WF, Yu ZL.(PubMed)
(559) Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits by Ma L1, Mao R1, Shen K1, Zheng Y1, Li Y1, Liu J2, Ni L3.(PubMed)
(560) The Treatment of Modern Western Medical Diseases with Chinese Medicine: A ... By Bob Flaws, Philippe Sionneau, page 364
(561) Literature-based analysis on relationship of symptoms, drugs and therapies in treatment of intestinal diseases by Gao L, Wang J, Li F, Deng Y, Gao S.(PubMed)
(562) The Treatment of Modern Western Medical Diseases with Chinese Medicine: A ... By Bob Flaws, Philippe Sionneau, page 346
(563) Fermented Rhizoma Atractylodis Macrocephalae alleviates high fat diet-induced obesity in association with regulation of intestinal permeability and microbiota in rats by Wang JH1, Bose S2, Kim HG3, Han KS3, Kim H3.(PubMed)
(564) Fu ling(Complementary and Alternative Healing University)
(565) Treatment of incipient diabetic nephropathy by clearing away the stomach-heat, purging the heart fire, strengthening the spleen and tonifying the kidney by Wu S1, Han Y, Li J.(PubMed)
(566) Ethanol extract of Poria cocos reduces the production of inflammatory mediators by suppressing the NF-kappaB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages by Jeong JW, Lee HH, Han MH, Kim GY, Hong SH, Park C, Choi YH1.(PubMed)
(567) Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions by Prieto JM1, Recio MC, Giner RM, Máñez S, Giner-Larza EM, Ríos JL.(PubMed)
(568) [Syndrome differentiation and treatment of Taiyang disease in Shanghan Lun].[Article in Chinese] by Yang X1, Peng WB, Yue XQ.(PubMed)
(569) Diuretic activity of some fractions of the epidermis of Poria cocos by Feng YL1, Lei P, Tian T, Yin L, Chen DQ, Chen H, Mei Q, Zhao YY, Lin RC.(PubMed)
(570) Diuretic activity of the ethanol and aqueous extracts of the surface layer of Poria cocos in rat by Zhao YY1, Feng YL, Du X, Xi ZH, Cheng XL, Wei F.(PubMed)
(571) Biological activities and potential health benefits of polysaccharides from Poria cocos and their derivatives by Sun Y1.(PubMed)
(572) Triterpenes from Poria cocos suppress growth and invasiveness of pancreatic cancer cells through the downregulation of MMP-7 by Cheng S1, Eliaz I, Lin J, Thyagarajan-Sahu A, Sliva D.(PubMed)
(573) Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos by Zhou L1, Zhang Y, Gapter LA, Ling H, Agarwal R, Ng KY.(PubMed)
(574) Antioxidant activity of carboxymethyl (1→3)-β-d-glucan (from the sclerotium of Poria cocos) sulfate (in vitro) by Wang Q1, Chen S2, Han L2, Lian M2, Wen Z2, Jiayinaguli T2, Liu L2, Sun R2, Cao Y3.(PubMed)
(575) Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs by Zhang L1, Ravipati AS, Koyyalamudi SR, Jeong SC, Reddy N, Bartlett J, Smith PT, de la Cruz M, Monteiro MC, Melguizo A, Jiménez E, Vicente F.(PubMed)
(576) Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential. by Wong KL1, Wong RN2, Zhang L1, Liu WK3, Ng TB3, Shaw PC4, Kwok PC5, Lai YM6, Zhang ZJ1, Zhang Y1, Tong Y1, Cheung HP1, Lu J1, Sze SC1.(PubMed)
(577) A activitiesUse of Yokukansan (TJ-54) in the treatment of neurological disorders: a review by de Caires S1, Steenkamp V.(PubMed)
(578) Over-the-counter sleeping pills: a survey of use in Hong Kong and a review of their constituents by Chung KF1, Lee CK.(PubMed)
(579) Antimicrobial activity of acid-hydrolyzed Citrus unshiu peel extract in milk by Min KY1, Kim HJ2, Lee KA1, Kim KT3, Paik HD4.(PubMed)
(580) New depside from Citrus reticulata Blanco by Phetkul U1, Phongpaichit S, Watanapokasin R, Mahabusarakam W(PubMed)
(581) Anti-fungal activity of Citrus reticulata Blanco essential oil against Penicillium italicum and Penicillium digitatum by Tao N1, Jia L2, Zhou H2.(PubMed)
(582) Phenolic compositions and antioxidant capacities of Chinese wild mandarin (Citrus reticulata Blanco) fruits by Zhang Y1, Sun Y, Xi W, Shen Y, Qiao L, Zhong L, Ye X, Zhou Z.(PubMed)
(583) Differential inhibition of human cancer cell proliferation by citrus limonoids by Tian Q1, Miller EG, Ahmad H, Tang L, Patil BS.(PubMed)
(584) EFFICACY OF CITRUS FRUIT PEEL EXTRACTS AGAINST PATHOGENS CAUSING GASTROINTESTINAL DISORDERS SRIVIDHYA. M1,2, RAMANATHAN. K2 AND KRISHNANAND. N.(International Journal of Pharmacy and Pharmaceutical Sciences)
(585) Chen pi(Complementary and Alternative Healing University)
(586) Encyclopedic Reference of Traditional Chinese Medicine edited by Yang Xinrong, page 542
(587) Ban xia(Complementary and Alternative Healing University)
(588) Effect of Pinellia ternata tuber on the efferent activity of the gastric vagus nerve in the rat.