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Tuesday, 22 April 2014

Food Therapy - Apricot and Colon cancer

The apricot tree is about 8–12 m tall and a trunk up to 40 cm diameter belongs to the family Rosaceae. Apricot is classified with the family of the plum and has yellow to orange, often tinged red on the side which is exposed to the sun.

Nutrients

1. Energy
2. Carbohydrates
3. Dietary fiber
4. Fat
5. Protein
6. Vitamin A
7. Beta-carotene
8. Vitamin C
9. Iron
10. Potassium
11. Tryptophan
12. Carotenoids
13. Etc.

Chemical constituents
Oleic acid, linoleic acid,  palmitic.acid, glycolipids, phospholipids, benzoic acid (I), isorhamnetin (II), quercetin (III), kaempferol-3-O-beta-D-galactopyranoside (IV), isorhamnetin-3-O-beta-D-glucopyranoside (V), isoquercitrin (VI), hypericin (VII) and rutin (VIII)(a) and flavonoid glycosides,  (b),
Apricot and Colon cancer
Bowel cancer also known as colorectal cancer, is defined as a condition of the abnormal proliferation of cells in the colon, rectum, or vermiform appendix. Bowl is divided in 2 parts, the first part of the bowel, the small bowl, is involved with the digestion and absorption of food. The 2nd part, the large bowel which consist the the colon and rectum, is involved in absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be re absorbed and reused by the body. Bowel cancer is relatively very common and slowly growing and progress cancer and in predictable way.
Bowel cancer is the third most commonly diagnosed cancer in developed countries, including U>S and Canada.

The study of anti-neoplastic effects of MK615, conducted by Dokkyo University School of Medicine, indicated a sginificant inbibited 3 colon cancer cell lines, SW480, COLO, and WiDr through its exertion of  induction of apoptosis and autophagy(1).


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References
(a) [Studies on the chemical constituents of flowers of Prunus mume].[Article in Chinese] by Zhang QH1, Zhang L, Shang LX, Shao CL, Wu YX.(PubMed)
(b) Flavonoid glycosides from Prunus armeniaca and the antibacterial activity of a crude extract.Rashid F1, Ahmed R, Mahmood A, Ahmad Z, Bibi N, Kazmi SU.(PubMed)


(1) New anti-proliferative agent, MK615, from Japanese apricot "Prunus mume" induces striking autophagy in colon cancer cells in vitro by Mori S1, Sawada T, Okada T, Ohsawa T, Adachi M, Keiichi K.(PubMed)